Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling

From Lab Bench Work to its Clinical Perspective

Asim K. Duttaroy, Rahul Mallick

• Publisher: Academic Press
• Year: 2024
• Print ISBN:
  9780323995702
• eBook ISBN:
  9780323995719
• Topic: Scienze biologiche
• Subtopic: Biologia

Cellular, Molecular and Environmental Contribution in Cardiac Remodeling: From Lab Bench to Clinical Perspective consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. It extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise and more. This book provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, and its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed. - Provides a concise summary of recent developments in cardiac remodeling research, combining novel information and the latest data published in this field - Discusses not only cellular and molecular factors impacting cardiac remodeling, but also environmental contributions such as lifestyle and exercise - Identifies areas for future research and potential novel strategies for translating basic research knowledge to applications in patients

Table of contents

• Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling: From Lab Bench Work to Its Clinical Perspective
• Chapter 1 Cardiac remodeling
• Chapter 2 Physiological cardiac modeling
• Chapter 3 Prognostic elements of unfavorable cardiac remodeling
• Chapter 4 Neurohormones in cardiac remodeling and function
• Chapter 5 Cardiokines and cardiac remodeling
• Chapter 6 Comparative effects of fatty acid and glucose in cardiac remodeling
• Chapter 7 Vitamins, minerals, and nutraceuticals
• Chapter 8 Junctional adhesion molecules
• Chapter 9 Composition and function of ion channels and their effects on cardiac remodeling
• Chapter 10 Notch signaling molecules
• Chapter 11 Neuregulin-1
• Chapter 12 Does endoplasmic reticulum stress break the heart?
• Chapter 13 Role of pattern recognition receptors in cardiac remodeling
• Chapter 14 Myocardial contractile proteins
• Chapter 15 Growth and proliferation of cardiomyocytes
• Chapter 16 Cardiac endothelial cells and their cross-talks with neighboring cells in cardiac remodeling
• Chapter 17 Pathophysiology of cardiac fibroblasts and impacts on the severity of the cardiac disease
• Chapter 18 Involvement of cardiac stem cells in cardiac remodeling or myocardial regeneration
• Chapter 19 Cardiac pericytes and cardiac remodeling
• Chapter 20 Macrophages in the remodeling of diseased heart
• Chapter 21 Inflammatory role of neutrophils in cardiac remodeling
• Chapter 22 Extracellular vesicle in cardiac remodeling
• Chapter 23 Long noncoding RNAs and miRNAs
• Index