Epigenetics in Human Disease
eBook - ePub

Epigenetics in Human Disease

  1. 1,334 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Epigenetics in Human Disease

About this book

Epigenetics in Human Disease, Third Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. From molecular mechanisms and epigenetic technology to clinical translation of recent research, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders, with an emphasis throughout on understanding and application of key concepts in new research and clinical practice. Fully revised and up-to-date, this Third Edition discusses topics of current interest in epigenetic disease research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, microRNA in cancer, epigenetic approaches to control obesity, epigenetics and airway disease, and epigenetics in cardiovascular disease. Further sections explore online epigenetic tools and datasets; early-life programming of epigenetics in age-related diseases; the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies. In addition, each chapter now includes chapter summaries, definitions, and vibrant imagery and figures to reinforce understanding, as well as step-by-step methods and disease research case studies. - Includes contributions from leading international investigators involved in translational epigenetic research and therapeutic applications - Integrates methods and applications with fundamental chapters on epigenetics in human disease, along with an evaluation of recent clinical breakthroughs - Presents side-by-side coverage of the basis of epigenetic diseases and treatment pathways - Each chapter updated to include summaries, definitions, and vibrant imagery and figures to reinforce understanding - Features step-by-step methods and disease research case studies to put book concepts into practice

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Yes, you can access Epigenetics in Human Disease by Trygve O Tollefsbol,Trygve O. Tollefsbol in PDF and/or ePUB format, as well as other popular books in Medicine & Genetics in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2023
Print ISBN
9780443218118
eBook ISBN
9780443218125
Edition
3
Topic
Medicine
Subtopic
Genetics in Medicine

Table of contents

  1. Cover
  2. Front Matter
  3. Table of Contents
  4. Translational Epigenetics Series
  5. Front Matter
  6. Copyright
  7. Contributors
  8. Contributors
  9. Preface
  10. Preface
  11. List of Illustrations
  12. List of Tables
  13. Chapter 1 : An overview of epigenetics of human disease
  14. Chapter 2 : Profiling histone posttranslational modifications and chromatin-modifying proteins by high-throughput reverse phase protein array
  15. Chapter 3 : Bioinformatics of epigenetic data generated from next-generation sequencing
  16. Chapter 4 : Alterations of histone modifications in cancer
  17. Chapter 5 : miRNAs as biomarkers breast cancer and their influence on tumor epigenetics
  18. Chapter 6 : Epigenetic biomarkers: Where are we in cancer therapy
  19. Chapter 7 : Epigenetics in neurobehavioral disease
  20. Chapter 8 : Emerging role of epigenetics in human neurodevelopmental disorders
  21. Chapter 9 : The epigenetics of neurodegenerative diseases
  22. Chapter 10 : Epigenetic basis of autoimmune disorders in humans
  23. Chapter 11 : Approaches to autoimmune diseases using epigenetic therapy
  24. Chapter 12 : Epigenomics and human obesity
  25. Chapter 13 : Transgenerational and early-life nutrition, epigenetics, and prevention of obesity
  26. Chapter 14 : Epigenetics of diabetes in humans
  27. Chapter 15 : The potential of epigenetic compounds in treating diabetes
  28. Chapter 16 : Epigenetic processesā€“driven disorders and therapeutics
  29. Chapter 17 : Epigenetics of allergic diseases: Allergies, eczema, asthma, and allergic rhinitis
  30. Chapter 18 : Nutrient intake, epigenetics, and asthma
  31. Chapter 19 : The role of epigenetics in cardiovascular disease
  32. Chapter 20 : Therapeutic potential of epigenetic drugs
  33. Chapter 21 : Epigenetics and human infectious diseases
  34. Chapter 22 : Therapy of infectious diseases using epigenetic approaches
  35. Chapter 23 : Translational aspects of the endometriosis epigenome
  36. Chapter 24 : Aberrant DNA methylation signatures in gynecological malignancies: Implications for early diagnosis, prognosis, and therapy
  37. Chapter 25 : Epigenetics in human reproduction and gynecologic diseases
  38. Chapter 26 : Epigenetics of transgenerational inheritance of disease
  39. Chapter 27 : Epigenomic mechanisms and episignature biomarkers in rare diseases
  40. Chapter 28 : Therapeutic approaches to imprinting diseases
  41. Chapter 29 : Stem cell epigenetics in development and disease
  42. Chapter 30 : Noncoding RNA regulatory networks, epigenetics, and programming stem cell renewal and differentiation: implications for stem cell therapy
  43. Chapter 31 : Aging and disease: the epigenetic bridge
  44. Chapter 32 : Epigenetic programming of human disease and aging
  45. Chapter 33 : Epigenetics, epidemiology, and public health
  46. Index for Volume 1
  47. Index for Volume 2