Medicinal Chemistry of Anticancer Drugs
eBook - ePub

Medicinal Chemistry of Anticancer Drugs

  1. 1,060 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Medicinal Chemistry of Anticancer Drugs

About this book

This third edition of Medicinal Chemistry of Anticancer Drugs, provides an updated resource for students and researchers from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. This new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theranostic anticancer agents, and pre-mRNA processing in cancer. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point of view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references to reviews and the primary literature. - Provides a resource that is organized consistently based on targets and mechanisms of action from a molecular point-of-view - Focuses on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents, providing a rationalization on the action of these type of drugs and the design of new active structures - Features a large number of color figures which give information in a clear-and-concise way - Includes extensive references to review articles and primary literature - Includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theragnostic anticancer agents, and pre-mRNA processing in cancer

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Yes, you can access Medicinal Chemistry of Anticancer Drugs by Carmen Avendaño,J. Carlos Menéndez in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Elsevier Science
Year
2023
eBook ISBN
9780128196526
Edition
3
Topic
Physical Sciences
Subtopic
Pharmacology

Table of contents

  1. Title of Book
  2. Cover image
  3. Medicinal Chemistry of Anticancer Drugs
  4. Title page
  5. Copyright
  6. Table of Contents
  7. Preface
  8. Abbreviations
  9. Chapter 1 General aspects of cancer therapy
  10. Chapter 2 Antimetabolites
  11. Chapter 3 Anticancer drugs that modulate hormone action
  12. Chapter 4 Anticancer strategies involving radical species
  13. Chapter 5 DNA alkylating agents
  14. Chapter 6 Anticancer drugs that interact with the DNA minor groove
  15. Chapter 7 DNA intercalation and topoisomerase inhibition
  16. Chapter 8 Epigenetic therapy of cancer
  17. Chapter 9 Anticancer drugs targeting tubulin and microtubules
  18. Chapter 10 Anticancer drugs acting on signaling pathways, part 1: Tyrosine kinase inhibitors
  19. Chapter 11 Anticancer drugs acting on signaling pathways, part 2: Inhibitors of serine-threonine kinases and miscellaneous signaling pathways
  20. Chapter 12 Protein degradation-based cancer therapy
  21. Chapter 13 Cancer immunotherapy
  22. Chapter 14 Miscellaneous small- molecule and biological approaches to targeted cancer therapy
  23. Chapter 15 Drug targeting in anticancer chemotherapy
  24. Chapter 16 Drugs that modulate resistance to antitumor agents
  25. Chapter 17 Cancer chemoprevention
  26. Index