Diagnostic Molecular Pathology
eBook - ePub

Diagnostic Molecular Pathology

A Guide to Applied Molecular Testing

  1. 768 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Diagnostic Molecular Pathology

A Guide to Applied Molecular Testing

About this book

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. - Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more - Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient - Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient - Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease

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Yes, you can access Diagnostic Molecular Pathology by William B. Coleman,Gregory J. Tsongalis in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Genetics & Genomics. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2023
Print ISBN
9780128228241
eBook ISBN
9780128229934
Edition
2
Topic
Biological Sciences
Subtopic
Genetics & Genomics
Index
Biological Sciences

Table of contents

  1. Cover
  2. Title page
  3. Table of Contents
  4. Copyright
  5. Dedication
  6. Contents
  7. List of contributors
  8. Preface
  9. List of Illustrations
  10. List of Tables
  11. Chapter 1 : Introduction to molecular testing in human disease
  12. Chapter 2 : Laboratory approaches in molecular pathology: the polymerase chain reaction
  13. Chapter 3 : Whole-exome and whole-genome sequencing in the molecular diagnostic laboratory
  14. Chapter 4 : Long-read sequencing for metagenomics in microbiology
  15. Chapter 5 : Molecular testing for human immunodeficiency virus
  16. Chapter 6 : Molecular testing in hepatitis virus-related disease
  17. Chapter 7 : Molecular testing for human papillomaviruses
  18. Chapter 8 : Molecular testing for parvoviruses
  19. Chapter 9 : Molecular testing for polyoma viruses
  20. Chapter 10 : Molecular testing for respiratory viruses
  21. Chapter 11 : Molecular testing for diseases associated with bacterial infections
  22. Chapter 12 : Agents associated with sexually transmitted infections
  23. Chapter 13 : Molecular methods for healthcare-acquired infections
  24. Chapter 14 : Molecular testing in emerging infectious diseases
  25. Chapter 15 : Molecular and serological testing in the setting of a global pandemic
  26. Chapter 16 : Noninvasive prenatal screening for fetal aneuploidies
  27. Chapter 17 : Molecular testing in inherited cardiomyopathies
  28. Chapter 18 : Molecular diagnostics for coagulopathies
  29. Chapter 19 : Molecular diagnosis of cystic fibrosis
  30. Chapter 20 : Molecular testing in hemochromatosis
  31. Chapter 21 : Molecular genetics of spinal muscular atrophy
  32. Chapter 22 : Molecular testing in autism spectrum disorder
  33. Chapter 23 : Molecular testing in breast cancer
  34. Chapter 24 : Molecular testing in lung cancer
  35. Chapter 25 : Molecular testing in colorectal cancer
  36. Chapter 26 : Molecular pathology and testing in melanocytic tumors
  37. Chapter 27 : Molecular testing for gliomas
  38. Chapter 28 : Molecular testing in pancreatic cancer
  39. Chapter 29 : Molecular testing in gynecologic cancer
  40. Chapter 30 : The emerging genetic landscape of renal cell carcinoma
  41. Chapter 31 : Molecular testing in thyroid cancer
  42. Chapter 32 : Molecular testing in pediatric cancers
  43. Chapter 33 : Molecular pathogenesis of soft tissue and bone tumors
  44. Chapter 34 : Molecular pathology of gastrointestinal stromal tumors
  45. Chapter 35 : Molecular pathology of hepatocellular carcinoma
  46. Chapter 36 : Molecular testing in myeloproliferative neoplasms
  47. Chapter 37 : Molecular testing in myelodysplastic syndromes
  48. Chapter 38 : Molecular testing in acute myeloid leukemia
  49. Chapter 39 : Molecular testing in the assessment of bone marrow transplant engraftment
  50. Chapter 40 : Pharmacogenomics in cardiovascular disease
  51. Chapter 41 : Personalized medicine for disorders of hemostasis and thrombosis
  52. Chapter 42 : Germline pharmacogenomics in cancer treatment
  53. Chapter 43 : Imaging mass spectrometry in clinical pathology
  54. Chapter 44 : Artificial intelligence and deep learning in molecular testing
  55. Chapter 45 : Nanotechnology for molecular diagnostics
  56. Chapter 46 : Chip-based nanotechnology in the molecular pathology laboratory and beyond
  57. Chapter 47 : Translational and clinical applications of the GeoMx digital spatial profiling platform
  58. Index
  59. A