Conceptual Breakthroughs in The Evolutionary Biology of Aging
eBook - ePub

Conceptual Breakthroughs in The Evolutionary Biology of Aging

  1. 296 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Conceptual Breakthroughs in The Evolutionary Biology of Aging

About this book

Conceptual Breakthroughs in the Evolutionary Biology of Aging continues the innovative Conceptual Breakthroughs series by providing a comprehensive outline of the major breakthroughs that built the evolutionary biology of aging as a leading scientific field. Following the evolutionary study of aging from its humble origins to the present, the book's chapters treat the field's breakthroughs one at a time. Users will find a concise and accessible analysis of the science of aging viewed through an evolutionary lens. Building upon widely-cited studies conducted by author Michael Rose, this book covers 30 subsequent years of growth and development within the field.The book highlights key publications for those who are not experts in the field, providing an important resource for researchers. Given the prevailing interest in changing the aging process dramatically, it is a powerful tool for readers who have a vested interest in understanding its causes and future control measures. - Reviews cell-molecular theories of aging in the light of evolutionary biology - Offers an evolutionary analysis of prospects for mitigating aging not commonly discussed within private and public sectors - Provides readers with a radically different perspective on contemporary biological gerontology, specifically through the lens of evolutionary biology

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Yes, you can access Conceptual Breakthroughs in The Evolutionary Biology of Aging by Kenneth R. Arnold,Michael R. Rose, John C. Avise in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2023
Print ISBN
9780128215456
eBook ISBN
9780128215463
Topic
Biological Sciences
Subtopic
Biology
Index
Biological Sciences

Table of contents

  1. Title of Book
  2. Cover image
  3. Title page
  4. Table of Contents
  5. Copyright
  6. Dedication
  7. Foreword from the Series Editor, John C. Avise
  8. Chapter One Introduction
  9. Chapter Two 384–322 B.C: The first biologist on aging
  10. Chapter Three 1645: A tale of two Bacons
  11. Chapter Four 1881: Natural selection is the ultimate determinant of aging
  12. Chapter Five 1922: Early laboratory experiments on demography
  13. Chapter Six 1928: Basic mathematics of selection with age-structure
  14. Chapter Seven 1930: First explanation of aging by age-specific patterns of selection
  15. Chapter Eight 1941: First proposal of the general idea of declining force of natural selection
  16. Chapter Nine 1946–57: Verbal hypotheses for the evolutionary genetics of aging
  17. Chapter Ten 1953: Absence of a Lansing effect in inbred Drosophila
  18. Chapter Eleven 1961: Presence of aging in a fish with continued adult growth
  19. Chapter Twelve 1966: Mathematical derivation of the forces of natural selection
  20. Chapter Thirteen 1960s: Falsification of the somatic mutation theory
  21. Chapter Fourteen 1960s: Falsification of the translation error catastrophe theory
  22. Chapter Fifteen 1968: Proposal of experimental designs to test evolutionary theories of aging
  23. Chapter Sixteen 1968: Accidental evolutionary postponement of aging
  24. Chapter Seventeen 1970: Experimental evolution of accelerated aging in Tribolium
  25. Chapter Eighteen 1970–74: Development of evolutionary genetics of age-structured populations
  26. Chapter Nineteen 1975: Application of Charlesworth's theory to the evolution of aging
  27. Chapter Twenty 1980: Full development of evolutionary genetic theory for aging
  28. Chapter Twenty One 1980–81: Quantitative genetic tests of hypotheses for the evolution of aging
  29. Chapter Twenty Two 1980–84: Mitigation of aging by postponing the decline in forces of natural selection
  30. Chapter Twenty Three 1977–1988: Characterization of Caenorhabditis elegans mutants with extended lifespan
  31. Chapter Twenty four 1982–85: Further mathematical characterization of evolution with antagonistic pleiotropy
  32. Chapter Twenty Five 1984: Genetic covariation is shifted to positive values by inbreeding
  33. Chapter Twenty Six 1984: Direct demonstration of nonaging in fissile species
  34. Chapter Twenty seven 1989: Additional experiments support antagonistic pleiotropy
  35. Chapter Twenty eight 1985: Genotype-by-environment interaction shown for aging
  36. Chapter Twenty nine 1985–onward: Evolutionary physiology of aging
  37. Chapter Thirty 1987: Accelerated senescence explained in terms of mutation accumulation with inbreeding depression
  38. Chapter Thirty one 1988: Reverse evolution of aging
  39. Chapter Thirty two 1985–88: Genetic analysis of aging in males
  40. Chapter Thirty three 1987–1991: Quantitative genetic analysis of how many genes determine aging
  41. Chapter Thirty four 1988: Evidence for senescence in the wild
  42. Chapter Thirty five 1989–onward: Molecular genetic variation at selected loci in the evolution of aging
  43. Chapter Thirty six 1988–89: The evolutionary logic of extending lifespan by dietary restriction
  44. Chapter Thirty seven 1992: Selection for stress resistance increases lifespan
  45. Chapter Thirty eight 1992: In late adult life, mortality rates stop increasing
  46. Chapter Thirty nine 1993–1995: Evolution of increased longevity among mammals, in the wild and the lab
  47. Chapter Forty 1993: Evolutionary physiology of dietary restriction
  48. Chapter Forty one 1993: Genetic association between dauer metabolic arrest and increased lifespan
  49. Chapter Forty two 1992–95: Experimental evolution of aging is connected to development
  50. Chapter Forty three 1994–96: Evidence for mutation accumulation affecting virility and aging
  51. Chapter Forty four 1996–98: Physiological research on evolution of aging supports organismal mechanisms
  52. Chapter Forty five 1996: Late-life mortality plateaus explained using evolutionary theory
  53. Chapter Forty six 1998–2003: Falsification of lifelong heterogeneity models for the cessation of aging
  54. Chapter Forty seven 1998–2000: Discovery of Drosophila mutants that sometimes increase longevity
  55. Chapter Forty eight 1999–2004: Nematode longevity mutants show antagonistic pleiotropy
  56. Chapter Forty nine 2002–06: Evolution of life-history fits evolutionary analysis of late life
  57. Chapter Fifty 2003–2005: Breakdown in correlations between stress resistance and aging
  58. Chapter Fifty one 2007–11: Development of demographic models that separate aging from dying
  59. Chapter Fifty two 2010: Studying the evolutionary origins of aging in bacteria
  60. Chapter Fifty three 2010: Genome-wide sequencing of evolved aging reveals many sites
  61. Chapter Fifty four 2011–19: Evolutionary transcriptomics also reveal complex physiology of aging
  62. Chapter Fifty five 2012: Late life is physiologically different from aging
  63. Chapter Fifty six 2014: Genomic studies of centenarians have low scientific power
  64. Chapter Fifty seven 2015: Evolutionary genetic effects produce two evolutionary biologies of aging
  65. Chapter Fifty eight 2016: Experimental evolution can produce nonaging young adults
  66. Chapter Fifty nine 2017: The heart is implicated in the evolution of aging
  67. Chapter Sixty 2020: Evolutionary adaptation to diet and its impact on healthspan
  68. Conclusion
  69. Glossary
  70. Author Index
  71. Index