Translational Radiation Oncology covers the principles of evidence-based medicine and applies them to the design of translational research. The book provides valuable discussions on the critical appraisal of published studies and recent developments in radiation oncology, allowing readers to learn how to evaluate the quality of such studies with respect to measuring outcomes and make effective use of all types of evidence. By reading this book, researchers have access to a practical approach to help them navigate challenging considerations in study design and implementation.It is a valuable resource for researchers, oncologists and members of biomedical field who want to understand more about translational research applied to the field of radiation oncology. Translational medicine serves as an indispensable tool in grant writing and funding efforts, so understanding how to apply its principles to research is necessary to guarantee that results will be impactful to patients.- Provides a clear process for understanding, designing, executing and analyzing clinical and translational research- Presents practical, step-by-step guidance to help readers take ideas from the lab to the bedside- Written by a team of oncologists, radiologists and clinical research experts that fully cover translational research in radiation oncology

Frequently asked questions

Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription.

No, books cannot be downloaded as external files, such as PDFs, for use outside of Perlego. However, you can download books within the Perlego app for offline reading on mobile or tablet. Learn more here.

Perlego offers two plans: Essential and Complete

Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.

Both plans are available with monthly, semester, or annual billing cycles.

We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1 million books across 1000+ topics, we’ve got you covered! Learn more here.

Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more here.

Yes! You can use the Perlego app on both iOS or Android devices to read anytime, anywhere — even offline. Perfect for commutes or when you’re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.

Yes, you can access Translational Radiation Oncology by Jeffrey A. Bakal, Daniel Kim, David Wazer, Adam E.M. Eltorai, Jeffrey A. Bakal,Daniel Kim,David Wazer,Adam E.M. Eltorai in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Year

Print ISBN

eBook ISBN

Topic

Subtopic

Index

Cover
Front Matter
Table of Contents
Handbook for Designing and Conducting Clinical and Translational Research
Copyright
List of contributors
Foreword
Preface
List of Illustrations
List of Tables
Chapter 1 : Introduction
Chapter 2 : Translational process
Chapter 3 : Scientific method
Chapter 4 : Basic research
Chapter 5 : Overview of preclinical research
Chapter 6 : What problem are you solving?
Chapter 7 : Types of interventions: drug, device, diagnostic, procedural technique, or behavior change
Chapter 8 : Drug discovery
Chapter 9 : Drug testing
Chapter 10 : Device discovery and prototyping
Chapter 11 : Device testing
Chapter 12 : Diagnostic discovery
Chapter 13 : Diagnostic testing
Chapter 14 : Procedural technique development in radiation oncology
Chapter 15 : Behavioral intervention studies in radiation oncology
Chapter 16 : Artificial intelligence
Chapter 17 : Introduction to clinical research: What is it? Why is it needed?
Chapter 18 : The question: types of research questions and how to develop them
Chapter 19 : Defining the study population: who and why?
Chapter 20 : Outcome measurements: What data are being collected and why?
Chapter 21 : Optimizing the question: Balancing significance and feasibility: Will the findings affect change? Can that change be implemented in clinical practice?
Chapter 22 : Statistical efficiency in study design
Chapter 23 : Basic statistical principles
Chapter 24 : Distribution
Chapter 25 : Hypotheses and error types
Chapter 26 : Power
Chapter 27 : Regression
Chapter 28 : Continuous variable analyses: t-test, Mann–Whitney, Wilcoxin rank
Chapter 29 : Categorical variable analyses: Chi-square, Fisher's exact, Mantel–Haenszel
Chapter 30 : Analysis of variance
Chapter 31 : Correlation
Chapter 32 : Biases
Chapter 33 : Methods and statistics for high-throughput data in basic science
Chapter 34 : Sample size
Chapter 35 : Statistical software
Chapter 36 : Design principles: hierarchy of study types
Chapter 37 : Case series: design, measures, classic example
Chapter 38 : Case-control study
Chapter 39 : Cohort studies
Chapter 40 : Cross-sectional study
Chapter 41 : Longitudinal studies
Chapter 42 : Meta-analysis: design, measures, real-world examples
Chapter 43 : A cost-effectiveness study: design, measures, classic example
Chapter 44 : Diagnostic test evaluation
Chapter 45 : Reliability study
Chapter 46 : Database studies
Chapter 47 : Surveys and questionnaires: design, measures, and classical examples
Chapter 48 : Qualitative methods and mixed-methods: design, measures, and classic examples
Chapter 49 : Visual analytics: design, measures, classic example
Chapter 50 : Randomized controlled trial
Chapter 51 : Nonrandomized trials in clinical oncology
Chapter 52 : Historical control: design and measures
Chapter 53 : Crossover study
Chapter 54 : Factorial design
Chapter 55 : Large, pragmatic: design, measures, classic example
Chapter 56 : Equivalence and non-inferiority trials: design, measures, classic example
Chapter 57 : Adaptive designs
Chapter 58 : Randomization: fixed or adaptive procedures
Chapter 59 : Blinding: who and why?
Chapter 60 : Phase 0 trials: windows of opportunity
Chapter 61 : Registries
Chapter 62 : Phases of clinical trials: overview
Chapter 63 : IDEAL framework for innovations in surgery
Chapter 64 : Patient perspectives
Chapter 65 : Ethics and review boards: Guiding principles, permissible and non-permissible questions, IRB process
Chapter 66 : Regulatory considerations for new drugs and devices
Chapter 67 : Funding approaches
Chapter 68 : Conflicts of interest
Chapter 69 : Clinical preparation—subject recruitment
Chapter 70 : Quality control
Chapter 71 : Translational radiation research—special populations
Chapter 72 : Case report forms
Chapter 73 : Subject adherence: are the subjects following the protocol? If not, how to assess and analyze (intention to treat vs. per protocol)
Chapter 74 : Survival analysis
Chapter 75 : FDA overview
Chapter 76 : Investigational New Drug Applications
Chapter 77 : New drug application
Chapter 78 : Regulatory basics - medical devices for the US market
Chapter 79 : Regulatory basics: radiation-emitting electronic products
Chapter 80 : Orphan drugs
Chapter 81 : Biologics License Application
Chapter 82 : Combination products
Chapter 83 : Chemistry, manufacturing, and controls
Chapter 84 : Postmarket drug safety monitoring
Chapter 85 : Postmarket device safety monitoring
Chapter 86 : Implementation research overview
Chapter 87 : Design and analysis
Chapter 88 : Mixed-methods research
Chapter 89 : Clinical guideline development
Chapter 90 : History of the Cooperative Group system (National Clinical Trials Network)
Chapter 91 : Digital health
Chapter 92 : Public health and cancer: an overview
Chapter 93 : Epidemiology
Chapter 94 : Multifactorial considerations of human health and public health in oncology
Chapter 95 : Good questions
Chapter 96 : Population and environmental-specific considerations
Chapter 97 : Public health law
Chapter 98 : Public health institutions and systems
Chapter 99 : Diversity, equity, and inclusion
Chapter 100 : Ethics in scientific publishing
Chapter 101 : Presenting data
Chapter 102 : Manuscript preparation
Chapter 103 : Promoting research
Chapter 104 : Social media and clinical trials
Chapter 105 : Quality improvement
Chapter 106 : Education to translate research into practice
Chapter 107 : Team science and building a team
Chapter 108 : Promoting research: why, how, indices h-index, m-index, etc
Chapter 109 : Venture Pathways for aspiring radiation oncologists
Chapter 110 : Developing Translational Ventures with the Federal Small Business Innovation Research/Small Business Technology Transfer (SBIR/STTR) Seed Funds
Chapter 111 : Sample forms and templates
Glossary
Index
A

About this book

Frequently asked questions

Information

Table of contents