Metabolic Syndrome

From Mechanisms to Interventions

Satinath Mukhopadhyay, Sunetra Mondal

• Publisher: Academic Press
• Year: 2023
• Print ISBN: 9780323857321
• eBook ISBN: 9780323856584
• Topic: Medicine
• Subtopic: Endocrinology & Metabolism

Metabolic Syndrome: From Mechanisms to Interventions covers all aspects of this complex and multifactorial disease, providing a cutting-edge understanding of the problem of MetS, with a particular focus on its prevention and clinical management. The book discusses practical implementable approaches to its reversal in clinical practice, encompassing the entire spectrum of MetS, from molecular understanding to clinical therapeutics and prevention. This book is a valuable resource for clinicians in multiple specialties, including endocrinologists, diabetologists, hepatologists, gynecologists and researchers in related fields who need a deep understanding of the full range of scientific and clinical aspects of metabolic syndrome. - Presents a holistic, preventative strategy involving each and every aspect of metabolic syndrome, from pathophysiologic to clinical management - Discusses recent research on the role of inflammation, adipokines and myokines in metabolic syndrome - Includes cutting-edge information on the impact of bariatric surgery and role of gut microbiota in MetS - Provides flowcharts and diagrams to simplify pathophysiologic aspects and their association between risk factors

Table of contents

• Metabolic Syndrome
• Cover
• Title Page
• Copyright
• Contents
• Dedication
• Contributors
• Foreword
• Chapter 1 Metabolic syndrome—A glance through the sands of time
• Chapter 2 Beyond the metabolic syndrome: Adverse influences of insulin resistance on the aging process
• Chapter 3 Intrauterine malnutrition and future risk of metabolic syndrome
• Chapter 4 Intervening at the stage of metabolic syndrome to prevent type 2 diabetes—Is it justified?
• Chapter 5 Dietary fats and their effects on metabolic syndrome and its components
• Chapter 6 Epidemiology of metabolic syndrome: global scenario
• Chapter 7 Epidemiology of metabolic syndrome in South and South-East Asia
• Chapter 8 Barker hypothesis and metabolic syndrome
• Chapter 9 Understanding the complexities of metabolic syndrome in First Nations Australians
• Chapter 10 Nutrition in the pathogenesis of metabolic syndrome: Roles of sugar, salt and fat
• Chapter 11 Vitamin D deficiency and metabolic syndrome—Is there a causality?
• Chapter 12 Role of inflammation in the pathogenesis of metabolic syndrome
• Chapter 13 Role of oxidative stress in the pathogenesis of metabolic syndrome
• Chapter 14 Mitochondrial dysfunction and metabolic syndrome
• Chapter 15 The entero-insular axis and metabolic syndrome
• Chapter 16 Type I interferons in metabolic syndrome
• Chapter 17 Role of circadian rhythms in metabolic syndrome
• Chapter 18 The role of genetic and epigenetic factors in familial clustering of metabolic syndrome
• Chapter 19 Endocrine disruptors in the pathogenesis of metabolic syndrome
• Chapter 20 Atherosclerotic cardiovascular disease in metabolic syndrome
• Chapter 21 Atherosclerosis is the outcome of adaptive complexity in the Arterial Endothelial Microenvironment
• Chapter 22 NAFLD, the hepatic manifestation of the metabolic syndrome
• Chapter 23 Obesity associated hypogonadism—a growing concern in metabolic syndrome
• Chapter 24 Sleep apnea—A cause or a consequence of metabolic syndrome?
• Chapter 25 Renal manifestations of metabolic syndrome: the link between obesity and chronic kidney disease
• Chapter 26 Metabolic syndrome and periodontitis: pathophysiologic links and clinical implications
• Chapter 27 Insulin resistance and risk of osteoporosis
• Chapter 28 Glucagon and the metabolic syndrome
• Chapter 29 Assessment of insulin resistance: From the bench to bedside
• Chapter 30 Role of exercise in the prevention and treatment of metabolic syndrome
• Chapter 31 Pharmacologic therapies in metabolic syndrome with special reference to non-alcoholic fatty liver disease
• Chapter 32 Role of newer anti-diabetes drugs in prediabetes: A systematic review
• Chapter 33 Management of insulin resistance in PCOS
• Chapter 34 The role of bariatric surgery in the management of metabolic syndrome
• Chapter 35 Anti-inflammatory interventions to mitigate the cardiovascular risk in metabolic syndrome
• Chapter 36 Management of new onset dysglycemia in transplant recipients
• Chapter 37 Management of lipid abnormalities in metabolic syndrome
• Chapter 38 Overview of metabolic syndrome in children and adolescents—an Indian perspective
• Chapter 39 Metabolic syndrome in children and adolescent: South Asian perspective
• Chapter 40 Inter-relationship between polycystic ovary syndrome and metabolic syndrome
• Chapter 41 Metabolic syndrome—definition
• Chapter 42 Metabolic syndrome and cancer risk
• Chapter 43 Obesity-mediated insulin resistance in target tissues: role of adiponectin, fetuin-A, and irisin
• Chapter 44 Gut microbiota and metabolic syndrome: What's new?
• Chapter 45 Metabolic syndrome and COVID-19: An unholy alliance
• Chapter 46 MicroRNA modulation in metabolic syndrome: A novel insight into cardiometabolic diseases
• Chapter 47 Role of artificial intelligence in tackling the metabolic syndrome pandemic
• Chapter 48 Glucose handling by the brain and its implication in metabolic syndrome
• Chapter 49 Hypoglycemia, insulin resistance, and cardiovascular disease: A possible link
• Chapter 50 Dietary interventions to combat obesity in metabolic syndrome - Role of time restricted eating
• Chapter 51 Systemic inflammation in psoriasis: Sequel of metabolic syndrome∗
• Chapter 52 Abdominal obesity and adipose tissue depots: Focus on intra-abdominal versus subcutaneous adipose tissue depots in Asian Indians
• Chapter 53 The immediate and long-term metabolic implications of maternal obesity and gestational weight gain
• Chapter 54 Managing the metabolic syndrome in a general practice setting in the UK (by a general practitioner practising among a high risk South Asian population)
• Index