Structure and Function of the Extracellular Matrix
eBook - ePub

Structure and Function of the Extracellular Matrix

A Multiscale Quantitative Approach

  1. 282 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Structure and Function of the Extracellular Matrix

A Multiscale Quantitative Approach

About this book

Structure and Function of the Extracellular Matrix: A Multiscale Quantitative Approach introduces biomechanics and biophysics with applications to understand the biological function of the extracellular matrix in health and disease. A general multiscale approach is followed by investigating behavior from the scale of single molecules, through fibrils and fibers, to tissues of various organ systems. Through mathematical models and structural information, quantitative description of the extracellular matrix function is derived with tissue specific details. The book introduces the properties and organization of extracellular matrix components and quantitative models of the matrix, and guides the reader through predicting functional properties. This book integrates evolutionary biology with multiscale structure to quantitatively understand the function of the extracellular matrix. This approach allows a fresh look into normal functioning as well as the pathological alterations of the extracellular matrix. Professor Suki's book is written to be useful to undergraduates, graduate students, and researchers interested in the quantitative aspects of the extracellular matrix. Researchers working in mechanotransduction, respiratory and cardiovascular mechanics, and multiscale biomechanics of tendon, cartilage, skin, and bone may also be interested in this book. - Examines the evolutionary origins and consequences of the extracellular matrix - Delivers the first book to quantitatively treat the extracellular matrix as a multiscale system - Presents problems and a set of computational laboratory projects in various chapters to aid teaching and learning - Provides an introduction to the properties and organization of the extracellular matrix components

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Yes, you can access Structure and Function of the Extracellular Matrix by Bela Suki in PDF and/or ePUB format, as well as other popular books in Technology & Engineering & Engineering General. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Structure and Function of the Extracellular Matrix
  2. Cover
  3. Title Page
  4. Copyright
  5. Table of Contents
  6. Dedication
  7. Preface
  8. Definition of symbols
  9. Chapter 1 Introduction to structure-function relationships
  10. Chapter 2 Extracellular matrix background material: Building blocks, general structure, mechanics, relation to cells, and evolutionary aspects
  11. Chapter 3 The collagen molecule
  12. Chapter 4 Collagen supramolecular structures: Evolution, organization, and biogenesis
  13. Chapter 5 Collagen suprastructures: The data and the models
  14. Chapter 6 Selected examples of tissue-level collagen suprastructures: Tendon, bone, and skin
  15. Chapter 7 Small leucine-rich proteoglycans: The tiny controllers of the extracellular matrix
  16. Chapter 8 Hyaluronan and hyalectans: The good, the bad, and the ugly
  17. Chapter 9 Elastic fibers: The near ideal linear springs of the extracellular matrix
  18. Chapter 10 Modeling maintenance and repair: The matrix loaded
  19. Chapter 11 Outlook
  20. Index