Translational Surgery
eBook - ePub

Translational Surgery

  1. 768 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Translational Surgery

About this book

Translational Surgery covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts including case-control studies, prospective cohort studies, randomized trials, and reliability studies. Investigators will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in surgical research, and know what is needed for collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the translational research navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in surgery, allowing the reader to learn how to evaluate the quality of such studies. Thus, they will improve at measuring outcomes; making effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every surgeon or surgical researcher who has ever had a good clinical idea, but not the knowledge of how to test it. - Focuses on translational research in Surgery, covering the principles of evidence-based medicine and applying those principles to the design of translational investigations - Provides a practical, straightforward approach to help surgeons and researchers navigate challenging aspects of study design and implementation - Details valuable discussions on the critical appraisal of published studies in Surgery, allowing the reader to effectively use all types of evidence for patient care

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Yes, you can access Translational Surgery by Adam E.M. Eltorai in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Surgery & Surgical Medicine. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Translational Surgery
  2. Cover
  3. Handbook for Designing and Conducting Clinical and Translational Research
  4. Title Page
  5. Copyright
  6. List of contributors
  7. Preface
  8. Acknowledgment
  9. Chapter 1 Introduction
  10. Chapter 2 Translational research process
  11. Chapter 3 Scientific method
  12. Chapter 4 Basic Research
  13. Chapter 5 Overview of preclinical research
  14. Chapter 6 What problem are you solving?
  15. Chapter 7 Types of intervention
  16. Chapter 8 Drug discovery and development
  17. Chapter 9 Drug testing: translating a novel immunotherapeutic from bench to bedside
  18. Chapter 10 Device discovery and prototyping
  19. Chapter 11 Medical device testing
  20. Chapter 12 Diagnostic discovery
  21. Chapter 13 Diagnostic testing
  22. Chapter 14 FDA regulating power & guidelines
  23. Chapter 15 Procedural technique development
  24. Chapter 16 Behavioral Interventions
  25. Chapter 17 Introduction to clinical research
  26. Chapter 18 The question
  27. Chapter 19 Study population
  28. Chapter 20 Outcome measurements
  29. Chapter 21 Optimizing the question
  30. Chapter 22 Basic statistical principles
  31. Chapter 23 Distributions
  32. Chapter 24 Hypothesis and error types
  33. Chapter 25 Power
  34. Chapter 26 Regression analysis
  35. Chapter 27 Continuous variable analyses
  36. Chapter 28 Categorical Variable Analyses
  37. Chapter 29 Analysis of variance
  38. Chapter 30 Correlation
  39. Chapter 31 Biases in research studies
  40. Chapter 32 Basic science statistics
  41. Chapter 33 Design principles
  42. Chapter 34 Case series
  43. Chapter 35 Case-control study—design, measures, and classic examples
  44. Chapter 36 Cohort study
  45. Chapter 37 Cross-sectional study
  46. Chapter 38 Longitudinal study
  47. Chapter 39 Designing clinical trials of surgical interventions
  48. Chapter 40 Meta-analysis
  49. Chapter 41 Cost-effectiveness research
  50. Chapter 42 Diagnostic test evaluation
  51. Chapter 43 Reliability study
  52. Chapter 44 Database research
  53. Chapter 45 Surveys and questionnaires
  54. Chapter 46 Qualitative methods and mixed methods
  55. Chapter 47 Randomized control
  56. Chapter 48 Nonrandomized control
  57. Chapter 49 Historical controls
  58. Chapter 50 Cross-over
  59. Chapter 51 Withdrawal studies
  60. Chapter 52 Factorial design
  61. Chapter 53 Group allocation
  62. Chapter 54 Hybrid design
  63. Chapter 55 Large, pragmatic trials
  64. Chapter 56 Equivalence and noninferiority
  65. Chapter 57 Adaptive
  66. Chapter 58 Principles and methods of randomization in research
  67. Chapter 59 Blinding
  68. Chapter 60 Multicenter considerations
  69. Chapter 61 Registries
  70. Chapter 62 Phases of clinical trials
  71. Chapter 63 IDEAL framework
  72. Chapter 64 Artificial intelligence methodology in clinical research
  73. Chapter 65 Patient perspectives
  74. Chapter 66 Sample size
  75. Chapter 67 Budgeting
  76. Chapter 68 Medical ethics and review boards
  77. Chapter 69 Regulatory considerations for new drugs and devices
  78. Chapter 70 Funding approaches
  79. Chapter 71 Subject recruitment
  80. Chapter 72 Data management
  81. Chapter 73 Quality control
  82. Chapter 74 Statistical software
  83. Chapter 75 Case report forms
  84. Chapter 76 Subject adherence
  85. Chapter 77 Survival analysis
  86. Chapter 78 Monitoring committees in clinical trials
  87. Chapter 79 FDA overview
  88. Chapter 80 Investigational new drugs
  89. Chapter 81 Drug development
  90. Chapter 82 Devices
  91. Chapter 83 Regulatory basics
  92. Chapter 84 Orphan drugs
  93. Chapter 85 Biopharmaceuticals
  94. Chapter 86 Combination products
  95. Chapter 87 Foods
  96. Chapter 88 Cosmetics
  97. Chapter 89 Non-US regulatory
  98. Chapter 90 Implementation research
  99. Chapter 91 Design and analysis
  100. Chapter 92 Population- and setting-specific implementation
  101. Chapter 93 Public health
  102. Chapter 94 Epidemiology
  103. Chapter 95 Factors in surgical public health and health disparities research
  104. Chapter 96 Good questions in public health research
  105. Chapter 97 Population and environmental specific considerations
  106. Chapter 98 Law, policy, and ethics
  107. Chapter 99 The role of healthcare institutions in translational surgical research
  108. Chapter 100 Public health institutions and systems
  109. Chapter 101 Data presentation
  110. Chapter 102 Manuscript preparation
  111. Chapter 103 Building a team
  112. Chapter 104 Patent basics
  113. Chapter 105 Venture pathways
  114. Chapter 106 Small Business Innovation Research and Small Business Technology Transfer
  115. Chapter 107 Sample forms and templates
  116. Index
  117. Index - Continued
  118. Index - Continued