
Nanotechnology Applications for Cancer Chemotherapy
- 702 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Nanotechnology Applications for Cancer Chemotherapy
About this book
Applications of Nanotechnology in Cancer Chemotherapy offers a complete and concise summary of nanotechnological interventions for cancer management. It highlights the basics of oncology, the cancer microenvironment, targets for active drug delivery, the underlying mechanisms and molecular pathways to enhance the drug delivery to the cancer site. The book discusses the principles of basic and innovative nanocarrier-based therapeutic approaches to modulate the progression of the disease. In addition, this book also explores the evolving targeting approaches specific to the cancer site and type.The scope of the book is not limited to targeted drug delivery for various cancers, but also explores the advancements in cancer imaging and diagnostics employing the nanotechnological tools. Emphasis has been given on the important evaluation techniques like in-vitro cell culture and in-vivo animal models to assess the performance of cancer nanomedicines. The book includes clinical study reports of various drug moieties explored using variety of nanoconstructs in myriad cancer conditions with the input of global market and pharmacoeconomics.- Discusses how organic and inorganic nanoplatforms are being used in cancer treatment- Shows how nanotechnology is being used to create new and more accurate diagnostic tools- Surveys the current generation of cancer nanomedicines, assessing their advantages and challenges
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Table of contents
- Cover image
- Title page
- Table of Contents
- Copyright
- Preface
- Chapter 1: Basic pathology and etiology of tumor
- Chapter 2: EPR effect and its implications in passive targeting of nanocarriers to tumors
- Chapter 3: pH-sensitive carriers for drug delivery to tumor sites
- Chapter 4: Temperature-sensitive carrier and temperature-directed tumor cell eradication
- Chapter 5: Magnetically responsive delivery into tumor environment
- Chapter 6: Ligands used for tumor targeting
- Chapter 7: Therapy targeting angiogenic potential of tumor
- Chapter 8: Immunotherapy of cancer
- Chapter 9: Chemical linkers: Potential approach to target tumor
- Chapter 10: Cell-penetrating peptides in cancer targeting
- Chapter 11: Inorganic nanoparticles: A new avenue in improving diagnostics
- Chapter 12: Development of photodynamic cancer therapy
- Chapter 13: Therapeutic based on small interfering RNA (siRNA)
- Chapter 14: Aptamer conjugates: A new avenue
- Chapter 15: Application of cancer stem cells in improving therapeutics
- Chapter 16: Targeting breast cancer
- Chapter 17: Lung cancer: Improving efficacy and reducing side effects
- Chapter 18: Colorectal cancer and its targeting
- Chapter 19: Hepatic cancer targeting
- Chapter 20: Solid tumor: Addressing the problems associated
- Chapter 21: Pancreatic cancer: Removing extracellular matrix barrier in delivery
- Chapter 22: Targeting to the CNS: Approach for brain tumor
- Chapter 23: Metastatic cancer: How one can address the therapeutic challenge
- Chapter 24: Prostate cancer: Delivery aspect and prospect
- Chapter 25: Leukemia: Trends in treatment and how close we have achieved eradication
- Chapter 26: Tumor imaging and its applications in tumor-targeted drug delivery
- Chapter 27: 2D and 3D cell culture: Getting close to mimicking the tumor microenvironment in vitro
- Chapter 28: In vivo animal models for cancer: What have we learned from chemical-induced and xenograft models
- Chapter 29: Nanosystem: Regulatory aspects, clinical development, and market potential
- Index