Synthesis of 6- and 7-Membered Heterocycles

The Role of DMF

Navjeet Kaur

• Publisher: Elsevier
• Year: 2023
• Print ISBN: 9780443161186
• eBook ISBN: 9780443161193
• Topic: Scienze fisiche
• Subtopic: Fisica

Synthesis of Six- and Seven-Membered Heterocycles: The Role of DMF and its Synthesis compares different synthetic approaches using DMF, including the advantages and disadvantages of those reactions, green methods, and the sustainability of reported synthetic methodologies, especially the microwave methods. The book presents several methodologies for the synthesis of six- and seven-membered heterocyclic compounds using dimethylformamide. Users will find the most up-to-date information in this fast-moving field which can be particularly challenging. With DMF drawing the attention of synthetic organic chemists, this book will help readers understand further developments in the uses of dimethylformamide beyond just its use as a polar solvent. As it can be expected that the use of dimethylformamide as a precursor will continue to grow in organic synthesis with new applications in sustainable and green chemistry, this book provides an ideal primer on the topics covered. - Compares different methods, reagents, reaction conditions, advantages and disadvantages - Discusses and compares different methodologies with green techniques - Includes reaction schemes, reaction mechanisms and the structure of reactive intermediates

Table of contents

• Synthesis of 6- and 7-Membered Heterocycles
• 1 Synthesis of pyridines
• 2 Synthesis of fused pyridines and piperidines
• 3 Synthesis of quinolines
• 4 Synthesis of isoquinolines
• 5 Synthesis of pyrimidines
• 6 Synthesis of pyridazines, pyrazines, quinazolines, quinoxalines, triazines, and tetrazines
• 7 Synthesis of pyrans and benzopyrans
• 8 Synthesis of fused benzopyrans
• 9 Synthesis of oxazines, benzoxazines, thiopyrans, and thiazines
• 10 Synthesis of azepines, diazepines, triazepines, oxepines, oxazepines, and thiapines
• Index