Cellular Endocrinology in Health and Disease

Alfredo Ulloa-Aguirre, Ya-Xiong Tao

• Publisher: Academic Press
• Year: 2021
• eBook ISBN: 9780128198025
• Edition: 2
• Topic: Biological Sciences
• Subtopic: Endocrinology & Metabolism
• Index: Biological Sciences

Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts - Explores endocrine cells biology in normal and pathologic conditions - Covers new aspects of endocrine cell function in distinct tissues - Provides a view into the biological effect in local and systemic levels - 15 new chapters covering the recent developments in the field

Table of contents

• Cellular Endocrinology in Health and Disease
• Cover
• Title Page
• Copyright
• Contents
• Contributors
• Preface to the Second Edition
• Chapter 1 Endocrinology of a Single Cell: Tools and Insights
• Chapter 2 Hypothalamic Cell Models
• Chapter 3 Biology of Pituitary Stem Cells
• Chapter 4 Epigenetics of Pituitary Cell Growth and Survival
• Chapter 5 Multi-functionality of Pituitary Cells: Biological and Clinical Implications
• Chapter 6 Unraveling the Neural Mechanisms Underlying the GnRH Pulse Generator: An Update
• Chapter 7 Gonadotropin-Releasing Hormone Receptors and Signaling
• Chapter 8 Effects of Nutrition on Pubertal Timing at the Neuroendocrine and Cellular Levels
• Chapter 9 Sensing Calcium Levels: The Biology of the Parathyroid Cells
• Chapter 10 GPCR Signaling in Ca2+ Homeostasis: The PTH Type 1 and Calcium-Sensing Receptors
• Chapter 11 Thyroid Hormone Receptors and their Role in Cell Proliferation and Cancer
• Chapter 12 Endocrine Regulation of Brown and Beige Adipose Tissue
• Chapter 13 Adiponectin and Adiponectin Signaling
• Chapter 14 Epigenetic and Developmental Basis of Risk of Obesity and Metabolic Disease
• Chapter 15 Cellular Basis of Insulin Resistance: A Tale of the Microvasculature
• Chapter 16 Endocrine Regulation of the Pancreas by Insulin-like Growth Factors
• Chapter 17 Transcriptome Analysis of Adrenocortical Cells in Health and Disease
• Chapter 18 Intracellular Trafficking of G Protein-Coupled Receptors to the Cell Surface Plasma Membrane in Health and Disease
• Chapter 19 LH/hCG and the Receptor: A Single Receptor for Two Ligands
• Chapter 20 The Follicle-Stimulating Hormone Signaling Network in Gonadal Cells
• Chapter 21 β-Arrestins and Endocrine-Related GPCRs
• Index