- 454 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Autophagy in Health and Disease
About this book
Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. It expands on the scope of the first edition by covering a wider range of cell types, developmental processes, and organ systems. The second edition is an international effort by investigators from 15 different countries whose many contributions are comprised in 28 chapters organized into six sections. The first section (Chapters 1-7) covers foundational concepts, including history, trajectory of the research field, mechanisms of autophagy, and autophagy regulation. The second section (Chapters 8-11) details developmental aspects, including stem cells, embryogenesis, hematopoiesis, and paligenosis. The subsequent sections are devoted to the role of autophagy in specific organ systems involved in metabolic control and diabetes (Chapters 12-15), the cardiovascular system (Chapters 16-18), and the nervous system (Chapters 19-20). The final section (Chapters 21-28) addresses autophagy in other organ systems vital to human health and longevity. Also included are chapters on microautophagy, chaperone-mediated autophagy, and the potential for autophagy as a therapeutic target.Autophagy in Health and Disease is invaluable to anyone new to the field as well as established investigators looking for a broader understanding of autophagy from outside their specific field of study.
- Provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathology
- Offers extended coverage of the mechanisms that mediate autophagy
- Covers the role of autophagy in stem cells and induced pluripotent stem cells, as well as the regenerative process of paligenosis
- Highlights important questions that remain to be addressed
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Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access Autophagy in Health and Disease by Beverly Rothermel,Abhinav Diwan in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Cell Biology. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Cover
- Front Matter
- Table of Contents
- Copyright
- Contributors
- About the editors
- Foreword
- Preface
- List of Illustrations
- List of Tables
- Chapter 1 : Introduction
- Chapter 2 : Mechanisms of autophagy: the machinery of macroautophagy and points of control
- Chapter 3 : Regulation of autophagy—transcriptional, posttranscriptional, translational, and posttranslational mechanisms
- Chapter 4 : Selectivity and trafficking of autophagic cargoes
- Chapter 5 : The role of lysosomes in autophagy
- Chapter 6 : Methods for measuring autophagy
- Chapter 7 : Effects of physiologic inputs on autophagy
- Chapter 8 : Autophagy in germ cells, stem cells, and induced pluripotent stem cells
- Chapter 9 : Role of autophagy in embryogenesis
- Chapter 10 : Autophagy in hematopoiesis and leukemogenesis
- Chapter 11 : Autophagy in cell plasticity with particular focus on paligenosis
- Chapter 12 : Autophagy in the liver
- Chapter 13 : Autophagy in adipose tissue
- Chapter 14 : Autophagy in the pancreas
- Chapter 15 : Skeletal muscle
- Chapter 16 : Autophagy in the cardiovascular system
- Chapter 17 : Lungs
- Chapter 18 : Autophagy in the vasculature
- Chapter 19 : Altered autophagy on the path to Parkinson's disease
- Chapter 20 : Autophagic processes in early- and late-onset Alzheimer's disease
- Chapter 21 : Autophagy as an integral immune system component
- Chapter 22 : Autophagy in the gastrointestinal system and cross talk with microbiota
- Chapter 23 : Role of autophagy in building and maintaining the skeletal system
- Chapter 24 : Autophagy on the road to longevity and aging
- Chapter 25 : Autophagy in cancer: friend or foe?
- Chapter 26 : Mammalian microautophagy: mechanism and roles in disease
- Chapter 27 : Chaperone-mediated autophagy—mechanisms and disease role
- Chapter 28 : Targeting autophagy: lifestyle and pharmacological approaches
- Index
- A