The Neurobiology of Aging and Alzheimer Disease in Down Syndrome
eBook - ePub

The Neurobiology of Aging and Alzheimer Disease in Down Syndrome

  1. 352 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

The Neurobiology of Aging and Alzheimer Disease in Down Syndrome

About this book

The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. - Discusses the complexities involved with aging and Alzheimer's disease in Down syndrome - Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age - Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research

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Yes, you can access The Neurobiology of Aging and Alzheimer Disease in Down Syndrome by Elizabeth Head,Ira Lott in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Geriatrics. We have over one million books available in our catalogue for you to explore.

Information

Table of contents

  1. Title of Book
  2. Cover image
  3. Title page
  4. Table of Contents
  5. Front Matter
  6. Copyright
  7. Dedication
  8. Contributors
  9. Acknowledgments
  10. Chapter 1 Introduction
  11. Chapter 2 Alzheimer's neuropathology in Down syndrome: From gestation to old age
  12. Chapter 3 The contribution of inflammation to Alzheimer's disease in Down syndrome
  13. Chapter 4 The role of cerebrovascular disease in aging and Alzheimer's disease among people with Down syndrome
  14. Chapter 5 Oxidative stress and mTOR in Down syndrome brain: Link to Alzheimer's dysmetabolism, neuropathology, and possible therapies
  15. Chapter 6 Fluid biomarkers for Alzheimer's disease in Down syndrome: Current status and novel trends
  16. Chapter 7 Proteomic and metabolomic biomarkers of Alzheimer's disease: Opportunities to advance precision medicine and clinical trials
  17. Chapter 8 Magnetic resonance imaging biomarkers for cognitive decline in Down syndrome
  18. Chapter 9 PET imaging in Down syndrome and Alzheimer's disease
  19. Chapter 10 Genetics of Alzheimer's disease in adults with Down syndrome
  20. Chapter 11 Co-occurring medical conditions in aging adults with Down syndrome
  21. Chapter 12 Sleep in aging adults with Down syndrome and its association with Alzheimer's disease
  22. Chapter 13 Contributions of the neurological examination to the diagnosis of dementia in Down syndrome
  23. Chapter 14 Psychiatric issues in aging and dementia
  24. Chapter 15 Cognitive profile of aging and dementia
  25. Chapter 16 Clinical trials for Alzheimer's disease in Down syndrome
  26. Chapter 17 Future directions
  27. Index