
- 308 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Proteolytic Signaling in Health and Disease
About this book
In recent years, powered by evolving technologies and experimental design, studies have better illuminated the regulating role of proteolytic enzymes across human development and pathologies. Proteolytic Signaling in Health and Disease provides an in-depth discussion of fundamental physiological and developmental processes regulated by proteases, from protein turnover and autophagy to antigen processing and presentation and major histocompatibility complex (MHC) molecules. Moving on from basic biology, international chapter authors examine a range of pathological conditions associated with proteolysis, including inflammation, wound healing, and cancer. Later chapters discuss the newly discovered network of connected events among proteases (and their inhibitors), the so-called 'protease web', and how best to study it. This book also empowers new research with up-to-date analytical methods and step-by-step protocols for studying proteolytic signaling events.
- Examines biological events triggered by proteolytic enzyme activity across human development and pathologies
- Discusses the role of proteolytic signaling in inflammation, wound healing, and cancer, among other disease types
- Features methods and protocols supporting further study of proteolytic signaling events
- Includes chapter contributions from international leaders in the field
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Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access Proteolytic Signaling in Health and Disease by Andre Zelanis in PDF and/or ePUB format, as well as other popular books in Scienze biologiche & Biochimica. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Title of Book
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter 1 Proteolytic signaling: An introduction
- Chapter 2 Ubiquitin ligases: Proteolytic signaling, protein turnover, and disease
- Chapter 3 Lysosomal proteases and their role in signaling pathways
- Chapter 4 Antigen processing and presentation through MHC molecules
- Chapter 5 Proteolytic processing in autophagy
- Chapter 6 Proteases are cut out to regulate acute and chronic inflammation
- Chapter 7 Proteolytic processing of laminin and the role of cryptides in tumoral biology
- Chapter 8 Proteolytic signaling in cutaneous wound healing
- Chapter 9 Proteinase imbalance in oral cancer and other diseases
- Chapter 10 “Omics” approaches to determine protease degradomes in complex biological matrices
- Chapter 11 The protease web
- Chapter 12 The puzzle of proteolytic effects in hemorrhage induced by Viperidae snake venom metalloproteinases
- Index