The Intestine
eBook - ePub

The Intestine

  1. 204 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

About this book

The intestine is among the leading organs, in which several cutting edge in vitro and in vivo research tools and approaches have recently been developed and used to investigate stem cell biology/function, and the potential applications of stem cells in the treatment of intestinal diseases. These cutting-edge research tools and approaches involve human and murine organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 1: The Intestine contains two major sections describing cutting edge research for understanding stem cell functions in the intestine, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model intestinal diseases, through the cutting-edge research, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of intestinal diseases/disorders. This volume, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the intestine in the real world. - Provides intensive scientific background and most recent information on cutting edge research to understand intestinal stem cell functions and develop methods to bring stem cells from bench to bedside for different intestinal diseases - Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and the CRISPR gene editing system in the intestine - Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the intestine

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Yes, you can access The Intestine by Ahmed El-Hashash,Eiman Abdel Meguid in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over one million books available in our catalogue for you to explore.

Information

Table of contents

  1. The Intestine
  2. Cover
  3. Title page
  4. Copyright
  5. Dedication
  6. Epigraph
  7. Contents
  8. List of contributors
  9. About the editors
  10. Foreword
  11. Foreword
  12. Preface
  13. Acknowledgments
  14. Chapter 1 Cutting-edge tools and approaches for stem cell research and application in intestinal diseases
  15. Chapter 2 Organotypic intestinal cell culture as a new modality for intestinal function and cellular processes
  16. Chapter 3 Role of human gastrointestinal organoids in discovery and translational medicine
  17. Chapter 4 Engineered stem cells combine stem cell and gene therapy approaches to move intestine therapy from bench to bed
  18. Chapter 5 Role of CRISPR/Cas9 and other gene editing/engineering technology in intestine diseases
  19. Chapter 6 Application of new approaches for intestinal repair and regeneration via stem cell–based tissue engineering
  20. Chapter 7 Induced pluripotent stem cells in intestinal diseases
  21. Chapter 8 Potential of embryonic stem cells for treating intestinal diseases
  22. Chapter 9 Stem-cell therapy with bone marrow (hematopoietic) stem cells for intestinal diseases
  23. Chapter 10 Role of mesenchymal and other stem cell therapy in intestinal diseases
  24. Chapter 11 General discussion, conclusion remarks, and future directions
  25. Index