
- 600 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Connectomic Deep Brain Stimulation
About this book
Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson's Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more.This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery.- Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery- Includes preprocessing strategies (such as co-registration, normalization, lead localization, VTA estimation and fiber-tracking approaches)- Presents references (key articles, books and protocols) for additional detailed study- Provides data analysis boxes in each chapter to help with data interpretation
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Information
Table of contents
- Cover
- Front Matter
- Table of Contents
- Copyright
- Contributors
- Foreword
- Preface
- Acknowledgments
- List of Illustrations
- List of Tables
- Chapter 1 : Connectomic DBS: An introduction
- Chapter 2 : Network neuroscience and the connectomics revolution
- Chapter 3 : Neurophysiological mechanisms of DBS from a connectomic perspective
- Chapter 4 : DBS imaging: An overview
- Chapter 5 : DBS imaging methods I: Preprocessing
- Chapter 6 : DBS imaging methods II: Electrode localization
- Chapter 7 : DBS imaging methods III: Estimating the electric field and volume of tissue activated
- Chapter 8 : Stereotactic spaces
- Chapter 9 : DBS imaging methods IV: Group analyses
- Chapter 10 : Resting-state functional MRI-based connectivity
- Chapter 11 : Diffusion MRI-based connectivity
- Chapter 12 : Normative connectomes and their use in DBS
- Chapter 13 : Investigating network effects of DBS with fMRI
- Chapter 14 : High-resolution resources and histological mesh tractography
- Chapter 15 : Using brain lesions to inform connectomic DBS
- Chapter 16 : Electrophysiological connectivity measures from deep brain stimulation (DBS)-targets in Parkinson’s disease and dystonia
- Chapter 17 : Mapping and predicting treatment response on a local level
- Chapter 18 : Predicting treatment response based on DBS connectivity
- Chapter 19 : Connectomic DBS in Parkinson’s disease, essential tremor and dystonia
- Chapter 20 : Connectomic DBS in major depression
- Chapter 21 : Connectomic deep brain stimulation in obsessive compulsive disorder
- Chapter 22 : Fiber tractography-assisted deep brain stimulation surgery: Connectomics in the operating room
- Chapter 23 : Investigating cognitive neuroscience concepts using connectomic DBS
- Chapter 24 : Combining invasive and noninvasive brain stimulation
- Chapter 25 : Outlook: Towards personalized connectomic deep brain stimulation
- Chapter 26 : Whole-brain modeling to predict optimal deep brain stimulation targeting
- Index
- A