Atkinson's Principles of Clinical Pharmacology
eBook - ePub

Atkinson's Principles of Clinical Pharmacology

  1. 762 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Atkinson's Principles of Clinical Pharmacology

About this book

**Selected for Doody's Core TitlesĀ® 2024 in Pharmacology**Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. - Presents the essential knowledge for effective practice of clinical pharmacology - Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology - Offers an extensive regulatory section that addresses US and international issues and guidelines - Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK

Frequently asked questions

Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription.
At the moment all of our mobile-responsive ePub books are available to download via the app. Most of our PDFs are also available to download and we're working on making the final remaining ones downloadable now. Learn more here.
Perlego offers two plans: Essential and Complete
  • Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
  • Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
Both plans are available with monthly, semester, or annual billing cycles.
We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1 million books across 1000+ topics, weā€™ve got you covered! Learn more here.
Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more here.
Yes! You can use the Perlego app on both iOS or Android devices to read anytime, anywhere ā€” even offline. Perfect for commutes or when youā€™re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access Atkinson's Principles of Clinical Pharmacology by Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson Jr. in PDF and/or ePUB format, as well as other popular books in Medicine & Biochemistry in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2021
eBook ISBN
9780128198841
Edition
4
Topic
Medicine
Subtopic
Biochemistry in Medicine

Table of contents

  1. Cover
  2. Front Matter
  3. Table of Contents
  4. Copyright
  5. Contributors
  6. Preface to the first edition
  7. List of Illustrations
  8. List of Tables
  9. Chapter 1 : Introduction to clinical pharmacology
  10. Chapter 2 : Clinical pharmacokinetics
  11. Chapter 3 : Compartmental analysis of drug distribution
  12. Chapter 4 : Drug absorption and bioavailability
  13. Chapter 5 : Effect of kidney disease on pharmacokinetics
  14. Chapter 6 : Pharmacokinetics in patients requiring renal replacement therapy
  15. Chapter 7 : Effect of liver disease on pharmacokinetics
  16. Chapter 8 : Noncompartmental and compartmental approaches to pharmacokinetic data analysis
  17. Chapter 9 : Population pharmacokinetics
  18. Chapter 10 : Pathways of drug metabolism
  19. Chapter 11 : Bioanalytical methods: Technological platforms and method validation
  20. Chapter 12 : Clinical pharmacogenetics
  21. Chapter 13 : Mechanisms and genetics of drug transport
  22. Chapter 14 : Drug-drug interactions
  23. Chapter 15 : Biochemical mechanisms of drug toxicity
  24. Chapter 16 : Pharmacogenomic mechanisms of drug toxicity
  25. Chapter 17 : Biomarkers in drug development
  26. Chapter 18 : Imaging in drug development
  27. Chapter 19 : Dose-effect and concentration-effect analysis
  28. Chapter 20 : Time course of drug response
  29. Chapter 21 : Disease progress models
  30. Chapter 22 : Sex-specific pharmacological differences
  31. Chapter 23 : Drug therapy in pregnant and nursing women
  32. Chapter 24 : Pediatric clinical pharmacology and therapeutics
  33. Chapter 25 : Medication therapy in older adults
  34. Chapter 26 : Clinical analysis of adverse drug reactions and pharmacovigilance
  35. Chapter 27 : Quality assessment of drug therapy
  36. Chapter 28 : Portfolio and project planning and management in the drug discovery, evaluation, development, and regulatory review process
  37. Chapter 29 : Drug discovery
  38. Chapter 30 : Nonclinical drug development
  39. Chapter 31 : Preclinical prediction of human pharmacokinetics
  40. Chapter 32 : Phase 1 clinical studies
  41. Chapter 33 : Pharmacokinetic and pharmacodynamic considerations in the development of biotechnology products and large molecules
  42. Chapter 34 : Design of clinical development programs
  43. Chapter 35 : The role of the FDA in guiding drug development
  44. Chapter 36 : Emerging clinical pharmacology topics in drug development and precision medicine
  45. Appendix I : Abbreviated table of Laplace transforms
  46. Appendix II : Answers to study problemsā€”Chapters 2ā€“5
  47. Index
  48. A