eBook - ePub
Redox Chemistry and Biology of Thiols
- 746 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Redox Chemistry and Biology of Thiols
About this book
Redox Chemistry and Biology of Thiols offers an applied, comprehensive overview of redox chemistry and biology of thiol-dependent processes. Running from basic biology and chemistry of redox phenomena to research methods and highlighting recently identified roles of thiols across cellular and bodily systems, this book draws upon a range of disciplines to illuminate new research directions, new applications of thiol studies, and clinical translation. Sections cover thiol oxidizing species, thiol reactivity and modifications, thioredoxin, glutaredoxin, glutathione, peroxidases, thiol repair enzymes, thiol oxidative signaling, disulfide bond formation, thiol-based redox biosensors, cysteine and hydrogen sulfide metabolism, iron-sulfur cluster biogenesis, thiols in chloroplasts, blood thiols, sugar and polyamine thiols in pathogenic organisms, redox medicine (therapeutic applications of thiols and drug development), as well as methods and bioinformatics tools.
- Runs from basic thiol biology and chemistry to applications and clinical translation
- Provides methods and protocols that will power new research across biomedicine, cell biology, plant biology, drug development, and protein folding and modulation
- Includes chapter contributions from international leaders in the field
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Table of contents
- Cover
- Front Matter
- Table of Contents
- Copyright
- Cover Credit
- Contributors
- Preface
- Acknowledgments
- List of Illustrations
- List of Tables
- Chapter 1 : Basic concepts of thiol chemistry and biology
- Chapter 2 : Chemical basis of cysteine reactivity and specificity: Acidity and nucleophilicity
- Chapter 3 : Computational functional analysis of cysteine residues in proteins
- Chapter 4 : Global approaches for protein thiol redox state detection and quantification
- Chapter 5 : Thiol oxidation by biologically-relevant reactive species
- Chapter 6 : Thiyl radicals: Formation, properties, and detection
- Chapter 7 : Detection of the oxidation products of thiols: Disulfides, and sulfenic, sulfinic, and sulfonic acids
- Chapter 8 : Biochemistry and detection of S-nitrosothiols
- Chapter 9 : Thiol modification and signaling by biological electrophiles
- Chapter 10 : Thioredoxin and glutathione reductases
- Chapter 11 : Functional plasticity in the thioredoxin family: FeS-thio- and glutaredoxins☆
- Chapter 12 : Glutathione and glutathione-dependent enzymes
- Chapter 13 : Thiol- and selenol-based peroxidases: Structure and catalytic properties
- Chapter 14 : Thiol peroxidase-based redox relays
- Chapter 15 : Compartmentalized disulfide bond formation pathways
- Chapter 16 : Disulfide bond formation in Escherichia coli
- Chapter 17 : Thiol-based redox probes
- Chapter 18 : Selenocysteine-containing proteins
- Chapter 19 : Overview of cysteine metabolism
- Chapter 20 : Hydrogen sulfide and persulfides
- Chapter 21 : The role of thiols in iron–sulfur cluster biogenesis
- Chapter 22 : Thiol-based redox control in chloroplasts
- Chapter 23 : Sugar-based cysteine thiols recruited for oxidative stress defense and redox regulation
- Chapter 24 : Polyamine-based thiols in pathogens
- Chapter 25 : Thiols in blood
- Chapter 26 : A thiol chemistry perspective on redox medicine
- Chapter 27 : Therapeutic applications of low-molecular-weight thiols and selenocompounds
- Chapter 28 : Thiol targets in drug development to combat bacterial infections
- Index
- A
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Yes, you can access Redox Chemistry and Biology of Thiols by Beatriz Alvarez,Marcelo Comini,Gustavo Salinas,Madia Trujillo in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biochemistry. We have over 1.5 million books available in our catalogue for you to explore.