Spine Phenotypes

Dino Samartzis, Jaro I. Karppinen, Frances M.K. Williams

• Publisher: Academic Press
• Year: 2022
• Print ISBN: 9780128227787
• eBook ISBN: 9780128227794
• Topic: Biological Sciences
• Subtopic: Biology
• Index: Biological Sciences

The era of big data and personalized spine care has arrived. Within that, imaging and clinical phenotypes are key in establishing personalized algorithms for patient care. This is particularly important in developing novel diagnostics and therapeutics as well as predicting outcomes and establishing preventative measures for various spinal disorders. Spine Phenotypes is a comprehensive resource that outlines phenotype descriptions, their imaging measurements and classifications, and provides an in-depth discussion regarding spine pathology and its clinical relevance. Multiauthored, with multidisciplinary contributions from world leaders in the field of imaging, spine research, and clinical practice, each chapter is rich in visual depiction of imaging phenotypes, providing examples of some established phenotypic measurements with a range of normal and pathologic images and their clinical implications. Spine Phenotypes will be a first of its kind reference for spine researchers, clinicians, and industry. - Book chapters devoted to specific imaging phenotypes with discussion of their clinical correlates - Imaging phenotypes provided with examples of established phenotypic measurements and a range of normal and pathologic images - Multiauthor, multidisciplinary contributions comprising world leaders in the field of spine imaging, research, and clinical practice

Table of contents

• Spine Phenotypes
• Cover
• Title Page
• Copyright
• Table of Contents
• Contributors
• Foreword
• Foreword by Jeremy Fairbank MD FRCS, Professor of Spine Surgery and Honorary Departmental Senior Research Fellow, NDORMS, University of Oxford, UK
• Preface
• Acknowledgments
• Acknowledgment
• 1 Anatomy of the spine
• 2 Biomechanics of the spine
• 3 Biomechanical models to study spinal phenotypes
• 4 Animal models to study spinal intervertebral disc phenotypes
• 5 Imaging technologies of the spinal discs
• 6 Intervertebral disc degeneration
• 7 Disc space narrowing and osteophytes
• 8 Displacement of intervertebral discs
• 9 High-intensity zones and annular tears
• 10 Vertebral endplate abnormalities, defects, and changes
• 11 Vertebral bone marrow (Modic) changes
• 12 Ossification of the posterior longitudinal ligament
• 13 Lumbar spinal stenosis
• 14 Facet joints
• 15 Paraspinal muscles
• 16 Spinal alignment
• Index