New Frontiers and Applications of Synthetic Biology

Vijai Singh

• Publisher: Academic Press
• Year: 2022
• Print ISBN:
  9780128244692
• eBook ISBN:
  9780323859868
• Topic: Biological Sciences
• Subtopic: Biology
• Index: Biological Sciences

New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas. - Offers basic understanding and knowledge in several aspects of synthetic biology - Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more - Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more

Table of contents

• Cover
• Title page
• Table of Contents
• Copyright
• Dedication
• Contents
• List of contributors
• About the editor
• Foreword
• Preface
• Acknowledgments
• List of Illustrations
• List of Tables
• Chapter 1 : An introduction to advanced technologies in synthetic biology
• Chapter 2 : Design and characterization of synthetic promoters
• Chapter 3 : Recent development in DNA synthesis technology
• Chapter 4 : Advances, challenges, and opportunities in DNA sequencing technology
• Chapter 5 : Recent developments in genome design and assembly tools
• Chapter 6 : Design, building, and challenges in synthetic genomics
• Chapter 7 : Synthetic minimal cells and their applications
• Chapter 8 : Small RNA-based systems for sensing and therapeutic applications
• Chapter 9 : High-throughput navigation of the sequence space
• Chapter 10 : Advances in protein engineering and its application in synthetic biology
• Chapter 11 : Computational tools for design of synthetic genetic circuits
• Chapter 12 : Computational tools for synthetic gene optimization
• Chapter 13 : De novo design and synthesis of biomolecules
• Chapter 14 : A retrobiosynthetic approach for production, conversion, sensing, dynamic regulation and degradation of molecules
• Chapter 15 : Advances in engineering of bacteriophages for therapeutic applications
• Chapter 16 : Design of synthetic biology for the detection of microorganisms
• Chapter 17 : Design of synthetic biological devices for detection and targeting human diseases
• Chapter 18 : Engineering cell-based therapies
• Chapter 19 : Development of next-generation diagnostic tools using synthetic biology
• Chapter 20 : Advances and application of CRISPR-Cas systems
• Chapter 21 : Synthetic biology for smart drug biosynthesis and delivery
• Chapter 22 : Design and applications of self-assembled soft living materials using synthetic biology
• Chapter 23 : Synthetic gene circuits for higher-order information processing
• Chapter 24 : Cell-free synthetic biology as an emerging biotechnology
• Chapter 25 : Recent development and applications of xeno nucleic acids
• Chapter 26 : Developments in the use of microfluidics in synthetic biology
• Chapter 27 : Implications of synthetic biology research and development: a structured ethical analysis
• Index
• A