Navigating Non-coding RNA
eBook - ePub

Navigating Non-coding RNA

From Biogenesis to Therapeutic Application

  1. 448 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Navigating Non-coding RNA

From Biogenesis to Therapeutic Application

About this book

Navigating Non-coding RNA: From Biogenesis to Therapeutic Application provides a concise overview of the field of non-coding RNA (ncRNA). Chapters cover the history of discoveries that have occurred in the area of ncRNA, specific types of ncRNA, housekeeping ncRNAs such as ribosomal RNA, transfer RNA, small nuclear RNA and telomerase RNA, regulatory ncRNAs such as microRNA, small interfering RNA, long non-coding RNA and Y RNA. Biogenesis, structure, function, and regulation of each of these are also explored in addition to traditional and cutting-edge methods for the identification, functional characterization and structural characterization of ncRNA. The book also focuses on the different types of epitranscriptomic modifications and their involvement in regulating ncRNA structure, stability and intermolecular interactions in addition to the role of ncRNAs in a range of diseases and potential therapeutic applications. - Covers a wide range of non-coding RNAs, including ribosomal RNA, transfer RNA, telomerase RNA, microRNA, small interfering RNA and circular RNA - Features both traditional and novel methodologies for investigating ncRNA, from microarray and conventional chemical probing to CAGE-seq and computational methods - Includes chapters on ncRNAs in a range of diseases, including cancers, neurological disorders, cardiovascular conditions and infectious illnesses - Discusses novel therapeutic strategies for targeting ncRNAs, including CRISP/Ca9 applications and RNAi-based strategies - Explores the molecular mechanisms and intermolecular interactions of ncRNA

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Yes, you can access Navigating Non-coding RNA by Joanna Sztuba-Solinska in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Molecular Biology. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Cover
  2. Front Matter
  3. Table of Contents
  4. Copyright
  5. List of contributors
  6. List of Illustrations
  7. List of Tables
  8. Chapter 1 : History and definitions of ncRNAs
  9. Chapter 2 : Regulatory non-coding RNAs-biogenesis, mechanisms of action and role in gene expression regulation
  10. Chapter 3 : Non-coding RNAs: Mechanisms of action
  11. Chapter 4 : Functional characterization of lncRNAs
  12. Chapter 5 : Secondary structural characterization of non-coding RNAs
  13. Chapter 6 : Regulation of non-coding RNAs
  14. Chapter 7 : Non-coding RNAs in human non-infectious diseases
  15. Chapter 8 : Non-coding RNAs in human infectious diseases
  16. Chapter 9 : Therapeutic targeting non-coding RNAs
  17. Index
  18. A