Chromatin Readers in Health and Disease
eBook - ePub

Chromatin Readers in Health and Disease

  1. 416 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Chromatin Readers in Health and Disease

About this book

Chromatin Readers in Health and Disease, Volume 35, a new release in the Translational Epigenetics series, gathers and makes actionable our current understanding of how chromatin readers regulate access to genetic information, and how their aberrant regulation can contribute to human pathologies. Chromatin readers discussed include 14-3-3 Dinshaw, ADD, Ankyrin, BAH, BET, BIR, BRCT, bromodomains and Kac readers, chromodomains and chromobarrel readers, citrullination readers, macrodomains and poly-ADP-ribose readers, MBT, PHD and double PHD, PWWP, SUMO (H4K12) readers, Tudor and TTD, UDR and ubiquitin, WD40, YEATS (crotonyl reader), MBD, SRA, and Methyl-RNA readers.In the book, more than a dozen leaders in the field examine a range of protein readers, their relationship to human disease, and the early therapeutics that act as chromatin signaling factors to treat cancers and Huntington's disease, among other disorders. - Enables researchers and clinicians to understand chromatin signaling mechanisms that regulate gene expression through chromatin readers - Highlights the role of chromatin readers in a variety of human pathologies, as well as early therapeutics that act on chromatin signaling - Includes chapter contributions from international leaders in the field

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Yes, you can access Chromatin Readers in Health and Disease by Olivier Binda, Trygve O Tollefsbol,Trygve O. Tollefsbol in PDF and/or ePUB format, as well as other popular books in Medicine & Genetics in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2023
Print ISBN
9780128233764
eBook ISBN
9780323903141
Topic
Medicine
Subtopic
Genetics in Medicine

Table of contents

  1. Chromatin Readers in Health and Disease
  2. Cover
  3. Translational Epigenetics Series
  4. Title Page
  5. Table of Contents
  6. Copyright
  7. Contributors
  8. Preface
  9. Chapter 1 ADD domains—A regulatory hub in chromatin biology and disease
  10. Chapter 2 The BAH domain: A versatile histone modification reader
  11. Chapter 3 BRCT domains as chromatin readers: Structure, function, and clinical implications
  12. Chapter 4 The bromodomain acyl-lysine readers in human health and disease
  13. Chapter 5 CHROMO domain readers: A rainbow of opportunities
  14. Chapter 6 The MBT proteins: Methyl-lysine readers for stem cells, development, and tumors
  15. Chapter 7 Epigenetically decipherING the genome: A role for PHDs
  16. Chapter 8 Recognition of histone methylation and DNA by the PWWP domain: Mechanism and function
  17. Chapter 9 Spin repeats and human pathologies
  18. Chapter 10 Chromatin readers of the WD-repeat containing protein family
  19. Chapter 11 The multifunctional YEATS domain in chromatin biology
  20. Chapter 12 DNA methylation and reader or writer proteins: Differentiation and disease
  21. Chapter 13 CUT&RUN and CUT&Tag: Low-input methods for genome-wide mapping of chromatin proteins
  22. Index