Cannabis Use, Neurobiology, Psychology, and Treatment

Colin R Martin, Vinood B. Patel, Victor R Preedy, Colin R. Martin

• Publisher: Academic Press
• Year: 2023
• Print ISBN: 9780323898621
• eBook ISBN: 9780323901406
• Topic: Biological Sciences
• Subtopic: Physiology
• Index: Biological Sciences

Cannabis Use, Neurobiology, Psychology, and Treatment offers readers a comprehensive reference on neurological changes, both transient and long-term, and other factors surrounding the use of these compounds and extracts. With coverage of both natural and synthetic cannabinoids, this broad coverage allows readers to learn about both adverse and non-adverse effects, including reactivity to pain, changes in behavior, and neuroactivity. This volume provides a platform for research on the effects of these compounds in brain function and neurological dysfunction. Extracts from the Cannabis sativa plant contain scores of psychoactive compounds in addition to the principal agent tetrahydrocannabinol, many of which are neuroactive. - Summarizes cannabis and cannabinoid research in relation to neurological function - Contains chapter abstracts, key facts, a dictionary and a summary - Covers the neuroactivity of multiple Cannabis compounds beyond tetrahydrocannabinol - Includes conditions like depression, anxiety, Parkinson's, psychosis, and epilepsy - Discusses brain structure and brain development, including functional connectivity

Table of contents

• Cover
• Front Matter
• Table of Contents
• Copyright
• Dedication
• Contributors
• Preface
• List of Illustrations
• List of Tables
• Chapter 1 : Metabolomics of the cannabis plant
• Chapter 2 : Cannabis sativa roots: Chemical and pharmacological profile
• Chapter 3 : Cannabis-related compounds in beverages and food
• Chapter 4 : The impact of prenatal cannabis exposure: An overview
• Chapter 5 : Cannabinoid genotoxicity and congenital anomalies: A convergent synthesis of European and USA data sets
• Chapter 6 : Cannabis genotoxicity and cancer incidence: Highly concordant synthesis of European and USA datasets
• Chapter 7 : Cannabis, cognitive impairment and car crash risk
• Chapter 8 : Recreational cannabis use: French perspective of adverse effects
• Chapter 9 : Acute and chronic impact of cannabis on human cognition
• Chapter 10 : Polydrug users, use of cannabinoids and abuse potential: A focus on cannabidiol (CBD)
• Chapter 11 : Cannabis stigmas: A narrative of features
• Chapter 12 : Alterations of THC and CBD ratios and impact on cognition
• Chapter 13 : When cannabis is used for medicinal purposes: A focus on back pain
• Chapter 14 : Cannabis, cannabinoids, and receptor responses
• Chapter 15 : Cannabidiol (CBD): Abuse and physical dependence potential
• Chapter 16 : 4,5-Dihydro-1H-pyrazole/3,4-Diarylpyrazoline class of cannabinoid-1 (CB1R) receptor antagonists and their potential in medicinal applications
• Chapter 17 : Neurobiology of the endocannabinoid system and relevance to cannabis use
• Chapter 18 : Neurobiology of the kynurenine pathway and cannabis misuse: A new narrative
• Chapter 19 : Central nervous system cancers and use of cannabis and related products: An updated narrative
• Chapter 20 : The relationship between glutamate and resting-state connectivity in chronic cannabis users
• Chapter 21 : Brain metabolic responses to cannabis use in people with multiple sclerosis: Insights from [18F]-FDG positron emission tomography and functional MRI
• Chapter 22 : Genetic variation and acute responses to cannabis
• Chapter 23 : Cell signaling of the CB1 cannabinoid receptor via β-arrestins, cannabinoid receptor interacting protein (CRIP1a) and other regulatory proteins
• Chapter 24 : Impact of cannabis on memory: From in utero to adulthood
• Chapter 25 : Age-related considerations in the use of cannabinoids: Focus on drug interactions, physiology, and drug effects
• Chapter 26 : Cannabis, binge drinking, and memory in adolescents and young adults
• Chapter 27 : The role of ΔFosB in the plasticity of the cannabinoid system
• Chapter 28 : Functional profile of synthetic cannabinoid receptor agonists: Exploring cannabinoid and noncannabinoid targets
• Chapter 29 : Linking the G-protein-coupled receptor 55 (GPR55) to the cannabinoid receptors (CB1 and CB2): A new narrative
• Chapter 30 : Proteomic analysis of cannabinoids in human oligodendrocyte cells
• Chapter 31 : Cannabinoids and endocannabinoid signaling at the basal forebrain cholinergic system
• Chapter 32 : Cannabidiol (the major nonpsychotropic cannabinoid in the cannabis plant) and the PI3K/AKT signaling pathway in the CNS
• Chapter 33 : Effects of cannabidiol and other phytocannabinoids on voltage- and ligand-gated ion channels
• Chapter 34 : Cannabis, neurodevelopment, and the “two-hit” hypothesis
• Chapter 35 : Impact of Δ9-tetrahydrocannabinol (THC) and synthetic “spice” cannabinoids on nicotine use and abuse
• Chapter 36 : Synthetic cannabinoid receptor agonists compared to Δ9-tetrahydrocannabinol: Neurological effects and beyond
• Chapter 37 : The DSM: 5 Criteria of cannabis use disorder: Methods and applications
• Chapter 38 : Cannabis and clinical high risk for psychosis: Monitoring and smartphones
• Chapter 39 : The impact of cannabis and cannabinoids on the skin
• Chapter 40 : Cannabis consumption in reproductive function and teratogenicity
• Chapter 41 : Phytocannabinoids have cytotoxic, antiproliferative, and antimigratory activities on cancer cells and cancer stem cells
• Chapter 42 : Motivational interviewing for cannabis use disorders: A narrative review from research to practice
• Chapter 43 : An overview of current pharmacologic interventions for management of cannabis withdrawal syndrome and the evidence for their use
• Chapter 44 : Managing cannabinoid hyperemesis syndrome in pediatrics: A new narrative review
• Chapter 45 : Gabapentinoids for the treatment of cannabis use disorder: A focus on human laboratory research
• Chapter 46 : Treating psychosis in users of synthetic cannabinoids
• Chapter 47 : Recommended resources for studying and investigating cannabis use, neurobiology, psychology, and treatments
• Index
• A