Oxetane Synthesis

Navjeet Kaur

• Publisher: Elsevier
• Year: 2023
• Print ISBN: 9780443189470
• eBook ISBN: 9780443189487
• Topic: Physical Sciences
• Subtopic: Pharmacology

Oxetane Synthesis rings play an important role as versatile motifs both in the overall formation of natural products and in synthetic organic chemistry. Oxetanes are important motifs in pharmaceutical chemistry that can confer improved metabolic and physicochemical properties. These developments continue to enhance the use of oxetanes in medicinal chemistry. Thanks to the growing commercial accessibility of oxetane possessing building blocks, together with improved approaches for the formation, oxetanes are likely to be progressively utilized in medicinal chemistry programs. Oxetanes are becoming valuable as a result of their vast diversity of uses in medicinal chemistry and varying applications. Several procedures have been developed for the formation and ring-opening of oxetanes to give important compounds in agrochemical, medicinal and material sciences. Novel approaches have been developed for the synthesis of oxetanes. These methods depend on both established synthetic approaches and development of many novel approaches for the formation of oxetanes. - Highlights methods for the synthesis of oxetanes - Includes new developments that enhance the use of oxetanes in medicinal chemistry - Covers new approaches recently developed for the synthesis of oxetanes

Table of contents

• Title of Book
• Cover image
• Title page
• Table of Contents
• Copyright
• Author biography
• Preface
• Abbreviations
• 1 Synthesis of oxetanes from epoxides
• 2 Synthesis of oxetanes from ketenes—Part I
• 3 Synthesis of oxetanes from ketenes—Part II
• 4 Synthesis of oxetanes from carbonyl compounds
• 5 Synthesis of oxetanes by addition of ene and yne compounds to carbonyl compounds
• 6 Synthesis of oxetanes from acid, alcohol, and carbonyl moiety-containing compounds
• 7 Synthesis of oxetanes from alcohols
• 8 Synthesis of oxetanes by addition of alkenes and alkynes to alcohols
• 9 Synthesis of oxetanes from diols
• 10 Synthesis of oxetanes from halo alcohols
• 11 Synthesis of oxetanes from alkenes under photochemical irradiation
• 12 Synthesis of oxetanes under photochemical irradiation
• 13 Synthesis of fused oxetanes under photochemical irradiation
• Glossary
• Index