
Aliphatic and Polyhalogenated Carcinogens
Structural Bases and Biological Mechanisms
- 618 pages
- English
- PDF
- Available on iOS & Android
Aliphatic and Polyhalogenated Carcinogens
Structural Bases and Biological Mechanisms
About this book
Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume IIIB: Aliphatic and Polyhalogenated Carcinogens covers environmentally and occupationally significant carcinogens of industrial origins. The book discusses the structure-activity relationships, metabolism, and environmental significance of the halogenated linear alkanes and alkenes and the halogenated cycloalkanes; and cycloalkene pesticides, biphenyls, and related aromatics. The text also describes the structure-activity relationships, metabolism, and environmental significance of the halogenated phenoxy acids, aromatic ethers, dibenzofurans, and dibenzo-p-dioxins; and ethylene glycol, diethylene glycol, dioxane, and related compounds. The structure-activity relationships, metabolism, and environmental significance of phenols and phenolic compounds; nitroalkanes and nitroalkenes; and acetamide, dimethylcarbamyl chloride, and related compounds thiocarbonyl compounds are also encompassed. The book further tackles the structure-activity relationships, metabolism, and environmental significance if fatty acids, detergents, and other surfactants with oncogenic potential. The text then looks into the effect of chemical reactivity, molecular geometry, and metabolism on carcinogenic activity. Chemists, geneticists, and those involved in cancer research will find the book invaluable.
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Table of contents
- Front Cover
- Aliphatic and Polyhalogenated Carcinogens
- Copyright Page
- Table of Contents
- Dedication
- General Plan
- Preface
- Acknowledgments
- Part III (Continued): STRUCTURE-ACTIVITY RELATIONSHIPS OF CHEMICAL CARCINOGENS. EFFECT OF CHEMICAL REACTIVITY, MOLECULAR GEOMETRY, AND METABOLISM ON CARCINOGENIC ACTIVITY
- 5. Structure-Activity Relationships
- UPDATING NOTES
- APPENDIX I: Novel Types of Carcinogens
- APPENDIX II: Update to Vol. I: New Developments in Short-Term Tests for Carcinogenicity: Genetic Toxicology
- APPENDIX III: Update to Vol. I: New Perspectives in Cancer Research Data Search: Modern Computer-Based Information
- APPENDIX IV: Update to Vol. IIA: Metabolic Activation by One-Electron and Two-Electron Oxidation in Aromatic Hydrocarbon Carcinogenesis
- Index