Drug Design

Medicinal Chemistry: A Series of Monographs, Vol. 4

E. J. Ariëns

• Publisher: Academic Press
• Year: 2013
• Print ISBN: 9780120603046
• eBook ISBN: 9781483216065
• Topic: Medicine
• Subtopic: Pharmaceutical, Biotechnology & Healthcare Industry

Drug Design, Volume IV covers the pharmaceutical phase of drug action, with emphasis on those aspects that are of importance in the design of optimally effective drug products. The book discusses biopharmaceutics as a basis for the design of drug products; the types and pharmacokinetics of peroral prolonged action dosage forms and parenteral prolonged action forms; and the design of topical drug products. The text also describes physical-chemical parameters which affect the bioavailability of topical drug products; the design of sunscreen preparations; as well as the clinical application of litholytic agents, which are preventive and curative drugs for nephrolithiasis. The design of biologically active nucleosides and of insecticidal chlorohydrocarbon derivatives is also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable.

Table of contents

• Front Cover
• Drug Design
• Copyright Page
• Table of Contents
• List of Contributors
• Preface
• Contents of Other Volumes
• Chapter 1. Biopharmaceutics as a Basis for the Design of Drug Products
• Chapter 2. Peroral Solid Dosage Forms with Prolonged Action
• Chapter 3. Parenteral Dosage Forms with Prolonged Action
• Chapter 4. Design of Topical Drug Products: Pharmaceutics
• Chapter 5. Design of Topical Drug Products: Biopharmaceutics
• Chapter 6. The Design of Sunscreen Preparations
• Chapter 7. Litholytic Agents: Preventive and Curative Drugs for Nephrolithiasis
• Chapter 8. The Design of Biologically Active Nucleosides
• Chapter 9. The Design of Insecticidal Chlorohydrocarbon Derivatives
• Author Index
• Subject Index