Biological Cycles

Current Topics in Cellular Regulation, Vol. 18

Ronald W. Estabrook, Paul A. Srere

• Publisher: Academic Press
• Year: 2013
• Print ISBN:
  9780121528188
• eBook ISBN:
  9781483217178
• Topic: Biological Sciences
• Subtopic: Biology
• Index: Biological Sciences

Current Topics in Cellular Regulation, Volume 18: Biological Cycles covers topics on the events of molecular biology, cellular communication, and the merging of cell structure to biochemical function. The book discusses the ornithin-urea cycle; the cycles of glutathione metabolism and transport; and the role of multienzymatic proteins in mammalian pyrimidine biosynthesis. The text also describes the significance of interconvertible enzyme cycles in cellular regulation; regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-dephosphorylation cycle; replenishment of citric acid cycle intermediates by the purine nucleotide cycle in rat skeletal muscle. The control of a secondary pathway of ethanol metabolism by differences in redox state; the role of aldolase and fructose bisphosphatase in the control of gluconeogenesis and glycolysis; and the fructose 6-phosphate/fructose 1,6-bisphosphate cycle are also considered. The book further tackles the cycles in polysaccharide biosynthesis and other important biological cycles. Biologists, microbiologists, cellular biologists, and biochemists will find the book invaluable.

Table of contents

• Front Cover
• Biological Cycles
• Copyright Page
• Table of Contents
• List of Contributors and Discussants
• Preface
• Excerpts from an Interview with Sir Hans Krebs
• Chapter 1. The Ornithine—Urea Cycle: Biosynthesis and Regulation of Carbamyl Phosphate Synthetase I and Ornithine Transcarbamylase
• Chapter 2. On the Cycles of Glutathione Metabolism and Transport
• Chapter 3. Multienzymatic Proteins in Mammalian Pyrimidine Biosynthesis: Channeling of Intermediates to Avoid Futile Cycles
• Chapter 4. Interconvertible Enzyme Cycles in Cellular Regulation
• Chapter 5. Regulation of Mammalian Pyruvate Dehydrogenase Complex by a Phosphorylation—Dephosphorylation Cycle
• Chapter 6. Replenishment of Citric Acid Cycle Intermediates by the Purine Nucleotide Cycle in Rat Skeletal Muscle
• Chapter 7. Control of a Secondary Pathway of Ethanol Metabolism by Differences in Redox State: A Story of the Failure to Arrest the Krebs Cycle for Drunkenness
• Chapter 8. Aldolase and Fructose Bisphosphatase: Key Enzymes in the Control of Gluconeogenesis and Glycolysis
• Chapter 9. The Fructose 6-Phosphate/Fructose 1,6-Bisphosphate Cycle
• Chapter 10. Cycles in Polysaccharide Biosynthesis
• Chapter 11. Tricarboxylic Acid Cycle Intermediates and the Control of Fatty Acid Synthesis and Ketogenesis
• Chapter 12. Ferroactivator and the Regulation of Gluconeogenesis
• Chapter 13. Metabolic Cycles in the Fermentation by Propionic Acid Bacteria
• Chapter 14. Sterol Structure and Membrane Function
• Chapter 15. The ATP- Phosphate Cycle
• CHapter 16. Formation and Utilization of PEP in Microbial Carbohydrate Transport
• Chapter 17. Cycles in the Function of Mitochondrial Membrane Transport Systems
• Chapter 18. The Cycling of Oxygen through Intermediates in the Cytochrome Oxidase—Oxygen Reaction
• Chapter 19. Energy Cycles in Health and Disease
• Chapter 20. The Glucose—Lactic Acid Cycle and Gluconeogenesis
• Chapter 21. Amino Acid Cycles in Man
• Chapter 22. Phosphorylation and Dephosphorylation of Glycogen Phosphorylase: A Prototype for Reversible Covalent Enzyme Modification
• Chapter 23. Role of Phosphorylation— Dephosphorylation Cycles in the Control of Protein Synthesis in Eukaryotes
• Chapter 24. Structure and Hormonal Regulation of the Ovalbumin Gene Cluster
• Chapter 25. Catabolite Repression in Yeast: Mediation by cAMP
• Chapter 26. Unwinding the Double Helix: Complete Equation for Chemical Equilibrium
• Chapter 27. The Structure and Evolution of Ribosomes and Their Components
• Chapter 28. A Cyclic Mechanism for Excitation and Adaptation
• Chapter 29. Protein Synthesis and Protein Turnover in Circadian Cycles
• Chapter 30. Membrane Cycling in Secretion: A Morphological Approach
• Chapter 31. Remarks in Honor of Professor Sir Hans Krebs
• Chapter 32. Response
• Index
• Contents of Previous Volumes