Frontiers of Bioorganic Chemistry and Molecular Biology

Proceedings of the International Symposium on Frontiers of Bioorganic Chemistry and Molecular Biology, Moscow and Tashkent, USSR, 25 September - 2 October 1978

S. N. Ananchenko

• Publisher: Pergamon
• Year: 2017
• Print ISBN:
  9780080239675
• eBook ISBN:
  9781483278834
• Topic: Biological Sciences
• Subtopic: Biology
• Index: Biological Sciences

Frontiers of Bioorganic Chemistry and Molecular Biology covers the proceedings of the International Symposium on Frontiers of Bioorganic Chemistry and Molecular Biology, held in Moscow and Tashkent, USSR on September 25-October 2, 1978. This symposium is devoted to a discussion of the physico-chemical basis of life processes. This book contains 56 chapters, and reflects the results in the study of peptides and proteins, nucleic acids, polysaccharides, and other biopolymers. Other chapters deal with the study of low molecular regulators, including steroids, alkaloids, and antibiotics. This book also includes discussion of the achievements in the study of genetic structures and of cellular protein synthesizing systems of the molecular basis of enzymic catalysis and of bioenergetic processes. This book will be of value to biochemists and molecular biologists.

Table of contents

• Front Cover
• Frontiers of Bioorganic Chemistry and Molecular Biology
• Copyright Page
• Table of Contents
• INTRODUCTORY SPEECH
• CHAPTER 1. INDICATIONS OF A COMMON REACTION MECHANISM OF ENZYMES CATALYZING THE HYDROLYSIS OF PYROPHOSPHATE BONDS
• CHAPTER 2. HIGHLIGHTS IN THE STUDY OF ENZYMIC AMINO GROUP TRANSFER: METABOLIC ROLE, STRUCTURE AND CATALYTIC MECHANISM OF TRANSAMINASES
• CHAPTER 3. THE ROLE OF SECONDARY SPECIFICITY IN CATALYSIS BY PROTEOLYTIC ENZYMES
• CHAPTER 4. ENZYME HAVING COVALENTLY BOUND FLAVINS
• CHAPTER 5. STRUCTURE AND EVOLUTION OF GLUTAMATE DEHYDROGENASES
• CHAPTER 6. STRUCTURAL AND FUNCTIONAL PROPERTIES OF CYTOCHROME C OXIDASE
• CHAPTER 7. GLYCOSYL TRANSFERASES IN OLIGOSACCHARIDE BIOSYNTHESIS AND THEIR USE IN STRUCTURE - FUNCTION ANALYSIS OF GLYCOPROTEINS
• CHAPTER 8. ENZYMES FOR SPLITTING AND SYNTHESIZING THE GLYCOSIDIC LINKAGES IN CARBOHYDRATE DETERMINANTS OF GLYCOPROTEINS
• CHAPTER 9. A VALINOMYCIN ANALOGUE CONTAINING ONLY NATURALLYOCCURRING AMINO ACIDS
• CHAPTER 10. TOXIC COMPONENTS FROM BUTHUS EUPEUS AND LUCOSA SINGORIENSIS VENOMS
• CHAPTER 11. PHYSIOLOGICAL SIGNIFICANCE OF THE CONSTITUENT POLYPEPTIDE CHAINS OF RICIN D
• CHAPTER 12. RECOGNITION OF PEPTIDE HORMONES AND KININS: MOLECULAR ASPECTS OF THE PROBLEM
• CHAPTER 13. SYNTHESIS AND STRUCTURE- FUNCTIONAL STUDIES ON HEME PEPTIDE MODELS OF NATURAL OXYGEN-BINDING HEMOPROTEINS
• CHAPTER 14. PROTEINS OF THE COTTONSEED
• CHAPTER 15. INSULIN-DEPENDENT CYTOPLASMIC REGULATOR SEPARATION, IDENTIFICATION AND INVESTIGATION OF INSULIN-LIKE ACTION
• CHAPTER 16. PROGRESS IN THE CHEMICAL SYNTHESIS OF PROINSULIN
• CHAPTER 17. MITOCHONDRIAL MEMBRANE-BOUND STEROID HYDROXYLATING SYSTEMS: STRUCTURE AND FUNCTIONS
• CHAPTER 18. ANALYSIS OF LOCAL ENVIRONMENT OF HISTIDINE RESIDUES IN PROTEINS BY HYDROGEN-TRITIUM EXCHANGE REACTION
• CHAPTER 19. THE CONFORMATIONS OBSERVED IN THE N TERMINAL A CHAIN RESIDUES OF INSULIN
• CHAPTER 20. GLOBULAR PROTEINS AND THEIR ASSOCIATIONS
• CHAPTER 21. COMPLEMENTATION OF PROTEIN CRYSTAL STRUCTURES BY NMR STUDIES IN SOLUTION
• CHAPTER 22. STUDIES OF ACID PROTEASE STRUCTURES BY MOLECULAR REPLACEMENT METHOD
• CHAPTER 23. DRUG METABOLISM AND THE FUNCTION OF CYTOCHROME P-450
• CHAPTER 24. CHANGES IN RAT LIVER GLYCOLYTIC REACTIONS DURING FLUOROACETATE POISONING
• CHAPTER 25. CHEMISTRY AND BIOCHEMISTRY OF THURINGIENSIN, A NATURAL ANALOGUE OF ATP
• CHAPTER 26. PROBLEMS OF STUDIES OF SPECIFIC CELL AUTOREGULATORS (ON THE EXAMPLE OF SUBSTANCES PRODUCED BY SOME ACTINOMYCETES)
• CHAPTER 27. BIOLOGICAL IMPLICATIONS OF RECENT DISCOVERIES IN THE MARINE STEROL FIELD
• CHAPTER 28. PROBLEMS OF REGULATION, SYNTHESIS AND METABOLISM OF NATURAL COMPOUNDS
• CHAPTER 29. SOME NEW RESULTS IN THE TOTAL SYNTHESIS OF ESTROGENS
• CHAPTER 30. SYNTHETIC APPROACHES TO 14-HYDROXYSTEROIDS
• CHAPTER 31. NEW PHYTOECDYSONES
• CHAPTER 32. THE PROBLEM OF DIVISION OF BIOLOGICAL FUNCTIONS OF ENDOGENOUS SUBSTANCES
• CHAPTER 33. EXTANT FLORA WITH RESPECT TO ITS CHEMISTRY
• CHAPTER 34. HORMONE-RECEPTOR INTERACTIONS: A STUDY OF THE MOLECULAR MECHANISM OF RECEPTOR STIMULATION IN ISOLATED FAT CELLS BY THE PARTIAL AGONIST CORTICOTROPIN-(5-24)-ICOSAPEPTIDE
• CHAPTER 35. MESSENGER RIBONUCLEOPROTEINS (INFORMOSOMES)
• CHAPTER 36. SELECTION OF mRNA INITIATION SITES FOR PROTEIN SYNTHESIS IN PROKARYOTES
• CHAPTER 37. THE RIBOSOMAL PEPTIDYL TRANSFERASE CENTER. POSSIBLE BASES FOR THE COMMON ACTION OF PEPTIDE BOND FORMATION INHIBITORS OF BACTERIAL AND EUKARYOTIC RIBOSOMES
• CHAPTER 38. AMINOACYL-tRNA SYNTHETASES: APPROACHES TO THE STRUCTURE AND FUNCTION OF THE ACTIVE CENTERS
• CHAPTER 39. DIVERSITY OF SUGAR PUCKER IN THE NUCLEIC ACIDS
• CHAPTER 40. THREE LEVELS OF CHROMATIN STRUCTURE
• CHAPTER 41. BIOSYNTHESIS AND PROPERTIES OF NORMAL AND MUTANT E. COLI RNA POLYMERASE
• CHAPTER 42. ISOLATION, CLONING AND STUDIES ON THE STRUCTURAL ORGANIZATION OF EUKARYOTIC GENES
• CHAPTER 43. PRIMARY ORGANIZATION AND FUNCTIONING OF THE NUCLEOSOME CORE PARTICLE OF CHROMATIN
• CHAPTER 44. POLYALKYLATING RNA COMPLEMENTARY TO SELECTED DNA AS A TOOL FOR GENE-DIRECTED MUTAGENESIS
• CHAPTER 45. EFFECTIVE SOLID PHASE METHOD FOR THE SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDES
• CHAPTER 46. E. COLI RNA-POLYMERASE INTERACTIONS WITH THE SUBSTRATES AND TEMPLATE THE PRIMARY STRUCTURES OF THE PHAGE 434 PROMOTERS
• CHAPTER 47. THE USE OF ULTRAVIOLET-INDUCED POLYNUCLEOTIDE-PROTEIN CROSSLINKS IN STUDIES OF NUCLEOPROTEIN STRUCTURE
• CHAPTER 48. STRUCTURAL STUDIES OF THE ELONGATION FACTOR G FROM ESCHERICHIA COLI
• CHAPTER 49. THE CYCLING OF Ca2+ ACROSS THE INNER MITOCHONDRIAL MEMBRANE
• CHAPTER 50. SOURCES OF ENERGY FOR MEMBRANE TRANSPORT IN YEASTS
• CHAPTER 51. LATERAL MOLECULAR MOTIONS IN MEMBRANES
• CHAPTER 52. APPEARANCE OF PHOTOINDUCED POTENTIAL ON PHOTORECEPTOR MEMBRANE
• CHAPTER 53. THE STUDY OF IONOPHORIC EFFECT OF SOME NEW DERIVATIVES OF CYCLIC POLYETHERS ON ARTIFICIAL AND BIOLOGICAL MEMBRANES
• CHAPTER 54. HEAVY WATER EFFECTS ON EXCITABLE MEMBRANES
• CHAPTER 55. MECHANISMS OF CELL ADHESION TO CELLULAR AND NON-CELLULAR SURFACES
• CHAPTER 56. BIOELECTROCATALYSIS AS A NEW PHENOMENON