Alcohol and Aldehyde Metabolizing Systems
eBook - PDF

Alcohol and Aldehyde Metabolizing Systems

Enzymology and Subcellular Organelles

  1. 472 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Alcohol and Aldehyde Metabolizing Systems

Enzymology and Subcellular Organelles

About this book

Alcohol and Aldehyde Metabolizing Systems, Volume II: Enzymology and Subcellular Organelles contains some of the papers presented at the Second International Symposium on Alcohol and Aldehyde Metabolizing Systems, held at the University of Pennsylvania in October 1976. Experts in the field from a wide variety of backgrounds tackled the problems of alcohol and aldehyde metabolism, discussed research findings, and examined controversial issues ranging from the molecular structure of enzymes to the clinical actions of alcohol in humans. Comprised of 43 chapters, this volume begins by comparing the enzymatically catalyzed oxidation of glyceraldehyde-3-phosphate and lactate, followed by an analysis of liver alcohol dehydrogenase and its mechanism of action. The reader is methodically introduced to the kinetics and mechanism of activated liver alcohol dehydrogenase; structural and functional changes in different alcohol dehydrogenases during evolution; and localization and properties of aldehyde reductase. Subsequent chapters deal with the correlation between the activity of acetaldehyde dehydrogenase and the structure of mitochondria; the distribution of subcellular organelles; and peroxisomes and microsomes. This book will be of value to practitioners and researchers from a variety of disciplines, including biochemistry, physiology, cell biology, and pharmacology.

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Yes, you can access Alcohol and Aldehyde Metabolizing Systems by Ronald G. Thurman,John R. Williamson,Henry R. Drott in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Zoology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2014
Print ISBN
9780126914023
eBook ISBN
9781483265469
Topic
Biological Sciences
Subtopic
Zoology
Index
Biological Sciences

Table of contents

  1. Front Cover
  2. Enzymology and Subcellular Organelles
  3. Copyright Page
  4. Table of Contents
  5. LIST OF PARTICIPANTS
  6. PREFACE
  7. CHAPTER 1. A COMPARISON OF THE ENZYMICALLY CATALYZED OXIDATION OF GLYCERALDEHYDE-3-PHOSPHATE AND LACTATE
  8. CHAPTER 2. MECHANISM OF ACTION OF LIVER ALCOHOL DEHYDROGENASE
  9. CHAPTER 3. EXTRAPOLATION OF MECHANISM STUDIES ON GLYCERALDEHYDE-3-PHOSPRATE DEHYDROGENASE TO THE TREATMENT OF AVIAN MUSCULAR DYSTROPHY
  10. CHAPTER 4. KINETICS AND MECHANISM OF ACTIVATED LIVER ALCOHOL DEHYDROGENASE
  11. CHAPTER 5. SOLVENT ISOTOPE EFFECTS IN THE YEAST ALCOHOL DEHYDROGENASE REACTION
  12. CHAPTER 6. KINETICS AND MECHANISM OF ACTIVATED LIVER ALCOHOL DEHYDROGENASE
  13. CHAPTER 7. SOLVENT ISOTOPE EFFECTS IN THE YEAST ALCOHOL DEHYDROGENASE REACTION
  14. CHAPTER 8. KINETICS OF NATIVE AND CHEMICALLY ACTIVATED HUMAN LIVER ALCOHOL DEHYDROGENASES
  15. CHAPTER 9. SUBSTRATE SPECIFICITY AND THE HYDROPHOBIC SITE OF LIVER ALCOHOL DEHYDROGENASE (L-ADH)
  16. CHAPTER 10. PROPERTIES OF HORSE LIVER ALCOHOL DEHYDROGENASE SS
  17. CHAPTER 11. ROOM AND LOW TEMPERATURE SPECTRAL IDENTIFICATION OF THE COBALT BINDINGS SITES IN LIVER ALCOHOL DEHYDROGENASE
  18. CHAPTER 12. HETEROGENEITY IN THE RAPIDLY EXCHANGING METALS OF HORSE LIVER ALCOHOL DEHYDROGENASE
  19. CHAPTER 13. MAGNETIC RESONANCE STUDIES OF THE INTERACTIONS OF IMIDAZOLE AND OTHER LIGANDS WITH COBALT SUBSTITUTED ALCOHOL DEHYDROGENASE FROM LIVER
  20. CHAPTER 14. WATER PROTON RELAXATION AND SPECTRAL STUDIES OF ALCOHOL DEHYDROGENASE PARTIALLY SUBSTITUTED WITH COBALT
  21. CHAPTER 15. INTERACTION AND ACTIVITIES OF NAD+ AND NAD+ ANALOGS WITH FOUR DEHYDROGENASES
  22. CHAPTER 16. MODIFICATION OF TRYPTOPHAN IN LIVER ALCOHOL DEHYDROGENASE
  23. CHAPTER 17. STRUCTURAL AND FUNCTIONAL CHANGES IN DIFFERENT ALCOHOL DEHYDROGENASES DURING EVOLUTION
  24. CHAPTER 18. METAL ΙΟΝ EFFECTORS OF HORSE LIVER ALDEHYDE DEHYDROGENASES
  25. CHAPTER 19. INTERACTION OF DISULFIRAM WITH HORSE LIVER ALDEHYDE DEHYDROGENASE
  26. CHAPTER 20. INTRACELLULAR LOCATION OF 3, 4-DIHYDROXYPHENYLACETALDEHYDE AND ACETALDEHYDE OXIDATION IN RAT LIVER
  27. CHAPTER 21. LOCALIZATION AND PROPERTIES OF ALDEHYDE REDUCTASE
  28. CHAPTER 22. HUMAN LIVER ALDEHYDE DEHYDROGENASE
  29. CHAPTER 23. INHIBITION OF RAT-LIVER ALDEHYDE DEHYDROGENASESIN VITRO AND IN VIVO BY DISULFIRAM, CYANAMIDE AND THEALCOHOL-SENSITIZING COMPOUND COPRINE
  30. CHAPTER 24. CORRELATION BETWEEN THE ACTIVITY OF ACETALDEHYDE DEHYDROGENASE AND THE STRUCTURE OF MITOCHONDRIA
  31. CHAPTER 25. INDUCTION1 OF CYTOSOLIC ALDEHYDE DEHYDROGENASE ISOZYMES: INFLUENCE ON ACETALDEHYDE METABOLISM
  32. CHAPTER 26. THE PLASTIC AND FLUID NATURE OF THE MITOCHONDRIAL ENERGY TRANSDUCING MEMBRANE
  33. CHAPTER 27. PEROXIDE GENERATION IN MITOCHONDRIA AND UTILIZATION BY CATALASE
  34. CHAPTER 28. METABOLISM OF H2O2 AND FATTY ACIDS BY RAT LIVER PEROXISOMES: IMPLICATIONS FOR ETHANOL DETOXIFICATION
  35. CHAPTER 29. SOME EFFECTS OF AGING AND LIPID-LOWERING DRUGSON LIPID METABOLISM AND THE HEPATIC ENDOPLASMIC RETICULUM
  36. CHAPTER 30. ON THE QUESTION OF WHETHER CYTOCHROME P-450 CATALYZES ETHANOL OXIDATION: STUDIES WITH PURIFIED FORMS OF THE CYTOCHROME FROM RABBIT LIVER MICROSOMES
  37. CHAPTER 31. EVIDENCE FOR THE DIRECT INVOLVEMENT OF HEPATIC CYTOCHROME P450 IN ETHANOL METABOLISM
  38. CHAPTER 32. ADVANTAGES OF GAS CHROMATOGRAPHIC DETERMINATION OF ACETALDEHYDE IN STUDIES WITH ETHANOL AND ARECONSTITUTED ENZYME SYSTEM CONTAINING ELECTROPHORETICALLY HOMOGENEOUS PHENOBARBITAL-INDUCIBLE CYTOCHROME P-450 FROM RABBIT LIVER MICROSOMES
  39. CHAPTER 33. RECONSTITUTION OF THE HEPATIC MICROSOMAL ETHANOL OXIDIZING SYSTEM (MEOS) IN CONTROL RATS AND AFTER ETHANOL FEEDING
  40. CHAPTER 34. MICROSOMAL ELECTRON TRANSPORT REACTIONS: THE FORMATION AND UTILIZATION OF HYDROGEN PEROXIDE AS RELATEDTO ALCOHOL METABOLISM
  41. CHAPTER 35. STUDIES ON THE CHARACTERIZATION OF THE ENZYME COMPONENTS PARTICIPATING IN THE HEPATIC-MICROSOMAL OXIDATION OF ALIPHATIC ALCOHOLS
  42. CHAPTER 36. QUANTITATION OF PATHWAYS RESPONSIBLE FOR NADPH-DEPENDENT METHANOL, ETHANOL, AND BUTANOL OXIDATION BY HEPATIC MICROSOMES
  43. CHAPTER 37. CATALASE AND ALCOHOL DEHYDROGENASE-MEDIATED OXIDATION OF ETHANOL IN HEPATIC MICROSOMES OF ACATALASEMIC MICE
  44. CHAPTER 38. ANALYSIS OF MITOCHONDRIAL AND MICROSOMALCYTOCHROMES IN HUMAN LIVER BIOPSY
  45. CHAPTER 39. A NOVEL ROUTE FOR THE METABOLISM OF ETHANOL;THE OXIDATION OF ETHANOL BY HYDROXYL FREE RADICALS
  46. CHAPTER 40. FOLATE DEFICXENCY AND METHANOL POISONING IN THE RAT
  47. CHAPTER 41. THE MONKEY AS A MODEL IN METHANOL POISONING
  48. CHAPTER 42. METHANOL POISONING: ROLE OF FORMATE METABOLISM IN THE MONKEY
  49. CHAPTER 43. MITOCHONDRIAL INJURY IN EXPERIMENTAL CHRONIC ALCOHOLISM
  50. INDEX