Biotechnological Production of Bioactive Phytochemicals of Medicinal Value

A Comprehensive Treatise

Anabela Romano, P. B. Kavi Kishor, Penna Suprasanna, T. Pullaiah, A. Ranga Rao, Anabela Romano, P. B. Kavi Kishor, Penna Suprasanna, T. Pullaiah, A. Ranga Rao, P.B. Kavi Kishor

• Publisher: Elsevier
• Year: 2024
• Print ISBN:
  9780443218187
• eBook ISBN:
  9780443218194
• Topic: Technology & Engineering
• Subtopic: Biology
• Index: Technology & Engineering

Plants are a source of bioactive compounds and specialty chemicals such as ginsenosides; paclitaxel, artemisinin, veregen and nutraceuticals. Biopharmaceuticals are important in human healthcare, and herbal actives are gaining importance all over the world. With natural resources dwindling, in vitro production of secondary compounds on a commercial scale is being more and more required. The difficulties that are increasingly encountered in procuring ample supply of raw plant material because of drastic decrease in natural resources have prompted the adaptation of in vitro technology for commercial production of substances of medicinal importance. Besides providing an alternative technology to bypass the above difficulties, the plant tissue culture (used in a broad sense to include cell, tissue and organ culture) offers many advantages. In vitro technology also facilitates novel means of conserving the genetic diversity of the germplasm of medicinal plants through cryopreservation, and production of novel compounds through biotransformation, somatic hybridization and selective gene transfer through recombinant DNA technology for enhancing the metabolite production. Biotechnological production of bioactive phytochemicals of medicinal value covers a broad variety of methods for secondary metabolites production (both pharmaceuticals and cosmeceuticals), compiling state-of-the-art material about the current knowledge of in vitro production for a large number of bioactive phytochemicals. - Compiles state-of-the-art material about in vitro production for several bioactive phytochemicals - Incorporates the most recent developments in the field - Covers a broad variety of secondary metabolites

Table of contents

• Cover
• Title page
• Table of Contents
• Copyright
• Contents
• List of contributors
• Preface
• List of Illustrations
• List of Tables
• Chapter 1 : Plants to pharmacy: recapitulation of natural compounds transmuting human health
• Chapter 2 : Production of bioactive metabolites in in vitro cultures of saffron (Crocus sativus L.)
• Chapter 3 : In vitro production of industrial valued bioactive secondary metabolites from selected medicinal plants of Sri Lanka
• Chapter 4 : In vitro production of secondary metabolites by Thymus plants
• Chapter 5 : In vitro production of anthocyanins
• Chapter 6 : Prospecting phytochemical and biological of seedling extract of Libidibia ferrea (Fabaceae) produced from in vitro propagation
• Chapter 7 : Properties, biotechnological production, and applications of rhinacanthins
• Chapter 8 : Nanoparticle-mediated elicitation of plant secondary metabolites, in vitro and in vivo
• Chapter 9 : Recent trends in in vitro production of alkaloids from Rauvolfia serpentina
• Chapter 10 : Experimental strategies to enhance in vitro production of plant secondary metabolites
• Chapter 11 : An overview of the in vitro synthesis of anthraquinones in plant cell and organ cultures and elicitation strategies
• Chapter 12 : Secondary metabolite production in transgenic cultures: an overview over the last decade
• Chapter 13 : In vitro production of phytoecdysteroids in plants
• Chapter 14 : Bacosides neurotropic molecules production by tissue cultures of Bacopa monnieri (L.) Wettst.
• Chapter 15 : Application of different tissue culture techniques for in vitro production of gymnemic acid: factors, approaches, and challenges to achieve higher yield
• Chapter 16 : Adoption of biotechnologies for Withania somnifera (L.) Dunal for sustainable utilization
• Chapter 17 : In vitro cultures of some Asclepiadaceae members: a source for the production of secondary metabolites
• Chapter 18 : In vitro studies and hairy root development with reference to secondary metabolite production in medicinally important Solanum erianthum D. Don
• Chapter 19 : A nonsteroidal antiinflammatory drug boswellic acid from Boswellia serrata Roxb.
• Chapter 20 : Accumulation of anticancer compounds in cultured cells and hairy roots
• Chapter 21 : Applications of radiations and mutagenesis for the enhancement of plant secondary metabolites
• Chapter 22 : In vitro hepatoprotective lignan production from Phyllanthus species
• Chapter 23 : Cardiotonic glycosides production in Digitalis: application of in vitro culture and transgenic approaches
• Chapter 24 : Production of bioactive compounds from cell and organ cultures of Centella asiatica
• Index
• A