Microbial Genomics: Clinical, Pharmaceutical, and Industrial Applications

Huseyin Tombuloglu, Amal Mahmoud, Huseyin Tombuloglu, Amal Mahmoud

• Publisher: Academic Press
• Year: 2024
• Print ISBN:
  9780443188664
• eBook ISBN:
  9780443188671
• Topic: Biological Sciences
• Subtopic: Genetics & Genomics
• Index: Biological Sciences

As the field of genomics has progressed, our understanding of microbiology has also developed. With the advent of next-generation sequencing methods and advancements in instrumental resolution, complex transcriptome, proteome, and metabolome data could be analyzed, as well as detailed annotation of microbial genomes. Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical and industrial fields. It consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics will be highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications. The book will be beneficial for researchers who study microbial genomics in universities, post-graduate and graduate programs (biology, biotechnology, medicine, genetics, microbiology, industrial and environmental microbiology, etc.), as well as the pharmaceutical and industrial sector. - Presents the recent genomic developments in the industrial applications of microorganisms - Summarizes recent developments in microbial genomics, emphasizing the role of next-generation sequencing in functional genomics - Focus on how transcriptomics can help better understand host responses to pathogen infection - Describes applications of genomics in clinical microbiology

Table of contents

• Microbial Genomics: Clinical, Pharmaceutical, and Industrial Applications
• Chapter 1 Introduction to microbial genomics
• Chapter 2 Viral genomics
• Chapter 3 Fungal genomics
• Chapter 4 Introduction to genomic-based clinical applications
• Chapter 5 Molecular techniques for the diagnosis of viral infections
• Chapter 6 Bacterial identification and diagnosis of bacterial infections through genomics, proteomics, nanotechnology, machine learning, and microelectromechanical systems
• Chapter 7 Fungal identification and diagnosis
• Chapter 8 Introduction to genomics-based pharmaceutical applications
• Chapter 9 Antiviral history and viral targets for antiviral therapy
• Chapter 10 Host- and genomics-based antiviral approaches
• Chapter 11 Antibiotic resistance and target-based technologies for drug development
• Chapter 12 Discovery and development of new antibacterial drugs
• Chapter 13 Potential targets for the development of antifungal drugs
• Chapter 14 Introduction to genomics-based industrial applications
• Chapter 15 Tailed phage machinery
• Chapter 16 Advances in fungal biotechnology in agriculture
• Index