Dosimetry for Radiopharmaceutical Therapy
eBook - ePub

Dosimetry for Radiopharmaceutical Therapy

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  1. 299 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Dosimetry for Radiopharmaceutical Therapy

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About this book

In this publication the basic principles of radiation physics, imaging and non-imaging instrumentation used, measurement of the administered activity, calibration procedures and methods for obtaining quantitative information on the biodistribution of the radioactive drug to be used with radioisotopes relevant to therapy are specified. It also describes methods for segmentation and registration of images acquired at different time points, strategies for fitting and integration of activity measurements over the time of treatment, absorbed dose calculations and derived dosimetric indexes with methods to estimate the overall uncertainty of different radionuclide therapies. The aim of this book is to fill the existing gaps in education and training of medical physicists on methods for patient-specific dosimetry. The overall objective of this book is to highlight the tools and methodologies to assure that radiopharmaceutical therapy is implemented through a dosimetry-guided individualized treatment approach.

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Table of contents

  1. Chapter 1INTRODUCTION
  2. Chapter 2PHYSICS
  3. Chapter 3METROLOGY — ACHIEVING ACCURATE AND CONSISTENT ABSORBED DOSE MEASUREMENT
  4. Chapter 4QUANTIFICATION OF ACTIVITY
  5. Chapter 5QUANTITATIVE IMAGING OF RADIONUCLIDES RELEVANT TO RADIOPHARMACEUTICAL THERAPY
  6. Chapter 6ANALYSIS OF TEMPORALLY VARYING DATA
  7. Chapter 7ABSORBED DOSE CALCULATION
  8. Chapter 8CLINICAL RADIOBIOLOGICAL MODELLING FOR RADIOPHARMACEUTICAL THERAPY
  9. Chapter 9UNCERTAINTY ANALYSIS
  10. Chapter 10RADIOPHARMACEUTICAL TREATMENT MODALITIES
  11. Chapter 11IMPLEMENTING DOSIMETRY IN THE CLINIC
  12. DEFINITIONS
  13. ABBREVIATIONS
  14. CONTRIBUTORS TO DRAFTING AND REVIEW