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Chemistry of Nucleic Acids
About this book
Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their structural analogues used as therapeutic drugs, such as antivirals and anticancer agents, and prodrug strategies of nucleotides.
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Yes, you can access Chemistry of Nucleic Acids by Harri Lönnberg in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biochemistry. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Preface
- Contents
- 1 Nucleosides: structure, nomenclature and solution equilibria
- 2 Nucleosides: synthesis, reactions and use in chemotherapy
- 3 Nucleotides
- 4 Oligonucleotides: synthesis
- 5 Oligonucleotides: reactions of phosphodiester linkages
- 6 Oligonucleotide conjugates
- 7 Nucleic acids
- 8 Catalytic nucleic acids
- 9 Nucleic acids as drugs and drug targets 1: antisense, splice-switching, triplex-forming and immune-stimulatory oligonucleotides
- 10 Nucleic acids as drugs and drug targets 2: RNA interference, 2′,5′-oligoadenylates and riboswitches
- 11 Nucleic acids as drugs and drug targets 3: target recognition and delivery
- Abbreviations
- Index