Molecular Targets and Therapeutic Interventions against Neurodegenerative Diseases

Vaishali Manikrao Patil, Dileep Kumar, NEERAJ MASAND

• Publisher: CRC Press
• Year: 2025
• Topic: Biological Sciences
• eBook ISBN:
  9781040310038
• Subtopic: Pharmacology
• Index: Biological Sciences

This book comprehensively explores the latest advancements in the understanding, diagnosis, and treatment of neurodegenerative diseases. The chapters provide an in-depth review of current approaches and treatment strategies for Alzheimer's disease, offering insights into the latest developments and breakthroughs. It also reviews the cutting-edge research on potential novel targets for Alzheimer's pharmacotherapy, with a focus on JNK3, GSK3?, and Fyn kinase inhibitors, providing an update on related approaches and their implications. It discusses the potential of ethnomedicines as a promising tool for mitigating Alzheimer's disease, offering insights into traditional remedies and their modern applications. Additional chapters explore the influence of microglia, the neuropharmacological mechanisms associated with SARS-CoV-2, and the molecular intricacies of Parkinson's disease. The book further covers the evolving role of artificial intelligence and machine learning in the management of neurodegenerative disorders. The chapters also examine the role of nanotechnology in addressing the challenges of diseases like multiple sclerosis. Towards the end, the book examines the role of oxidative damage in neurodegeneration and its management in related disorders. This book is an important source for neuroscientists, neurologists, and students of neuroscience.

Table of contents

• Cover
• Half-Title
• Title
• Copyright
• Contents
• Preface
• About the Editors
• Contributors
• Chapter 1 Comprehensive Review on Alzheimer’s Disease: Recent Approaches and Treatment Strategies
• Chapter 2 Novel Molecular Targets at the Forefront of Neurodegenerative Research
• Chapter 3 Potential Novel Targets for Alzheimer’s Pharmacotherapy: Update on JNK3, GSK3β, and Fyn Kinase Inhibitors and Related Approaches
• Chapter 4 The TREM2 Receptor Puzzle in Alzheimer’s Disease: Assembling the Pieces
• Chapter 5 Phosphodiesterase: A Safe and Potential Target for Anti-Alzheimer’s Therapeutics
• Chapter 6 The NMDA Receptor Hypothesis in Alzheimer’s Disease: Unraveling the Mechanisms
• Chapter 7 Artificial Intelligence and Machine Learning-Based Advances in the Management of Neurodegenerative Diseases
• Chapter 8 Microglia, a New Avenue in the Cure and Treatment of Alzheimer’s Disease
• Chapter 9 Neuropharmacological Mechanisms of SARS-CoV-2
• Chapter 10 Current Perspectives on Pyrazole Scaffolds and Their Potential Impact on Alzheimer’s Disease
• Chapter 11 Role and Therapeutic Perspectives of Oxidative Stress in Neurodegenerative Diseases
• Chapter 12 Herbs and Natural Products for Neurodegenerative Disorders
• Chapter 13 Role of Nanotechnology in Multiple Sclerosis
• Chapter 14 Therapeutic Advancement in the Treatment of Neurodegenerative Diseases
• Chapter 15 Recent Developments in Nanotechnology-Based Therapeutics for the Treatment of Alzheimer’s Disease
• Index