Advanced Drug Delivery Systems in Management of Chronic Obstructive Pulmonary Disease

Parteek Prasher, Mousumee Sharma, Gang Liu, Amlan Chakraborty, Kamal Dua

• Publisher: CRC Press
• Year: 2025
• eBook ISBN: 9781040314265
• Edition: 0
• Topic: Medicine
• Subtopic: Pulmonary & Thoracic Medicine

This book offers a comprehensive overview of the epidemiology, etiology, and pathophysiology of chronic obstructive pulmonary disease (COPD). It addresses the limitations of existing drug delivery methods and explores advanced delivery systems to overcome these challenges, providing an exhaustive account of their intricate mechanisms. The introductory chapters elucidate pathways responsible for COPD progression, followed by a detailed analysis of established biomarkers and potential targets in contemporary COPD therapy. Subsequent chapters provide insights into ongoing treatment modalities, their efficacy, drawbacks, and prospective solutions to counter the setbacks of COPD therapy. The subsequent section covers state-of-the-art drug delivery technologies and novel drug formulations designed to enhance drug deposition and absorption in COPD lungs. It further explores a methodical yet coordinated explanation of targeted personalized therapies and emerging approaches, including nanoparticles, polymeric carriers, and vesicular delivery systems. Toward the end, the book discusses ongoing and completed clinical trials encompassing the management of COPD through advanced drug delivery approaches. It serves as a valuable resource for professionals, scientists, academicians, and clinicians specializing in respiratory health.

• Provides an in-depth understanding of the epidemiology, etiology, and pathophysiology of Chronic Obstructive Pulmonary Disease (COPD)
• Delve into pathways responsible for COPD progression, conducting a detailed analysis of established biomarkers and potential targets in contemporary COPD therapy
• Offer insights into ongoing treatment modalities, evaluating their efficacy, drawbacks, and proposing prospective solutions to counter the setbacks of COPD therapy
• Systematically organizes information on state-of-the-art drug delivery technologies and novel formulations designed to enhance drug deposition and absorption in COPD lungs
• Presents a methodical explanation of targeted personalized therapies and emerging approaches, including nanoparticles, polymeric carriers, and vesicular delivery systems

Table of contents

• Cover Page
• Half-Title Page
• Title Page
• Copyright Page
• Contents
• About the Editors
• List of Contributors
• Chapter 1 Introduction to COPD: Epidemiology, Etiology, and Pathophysiology
• Chapter 2 Biomarkers for the Management of Chronic Obstructive Pulmonary Disease
• Chapter 3 Current Treatment Modalities for Chronic Obstructive Pulmonary Disease: Challenges and Limitations
• Chapter 4 Inhalation Drug Delivery Systems for the Management of Chronic Obstructive Pulmonary Disease
• Chapter 5 Advancements in Smart Inhaler Technology for Enhancing Chronic Obstructive Pulmonary Disease Care
• Chapter 6 Nanotechnology in Pulmonary Drug Delivery Systems
• Chapter 7 Liposomal Drug Delivery for the Management of Chronic Obstructive Pulmonary Disease
• Chapter 8 Polymeric Nanoparticles for Targeted Therapy of Chronic Obstructive Pulmonary Disease
• Chapter 9 Hybrid Nanocarriers for the Delivery of Therapeutics in Chronic Obstructive Pulmonary Disease
• Chapter 10 Dendrimers as Emerging Drug Carriers in Chronic Obstructive Pulmonary Disease
• Chapter 11 Biodegradable Polymers for Controlled Release of Drugs in Chronic Obstructive Pulmonary Disease
• Chapter 12 Nano Approaches for the Delivery of Biologics in Chronic Obstructive Pulmonary Disease
• Chapter 13 Nanotheranostics for Chronic Obstructive Pulmonary Disease (COPD): Status and Implications
• Chapter 14 Senolytics: A Potential Therapeutic Approach for COPD Management
• Chapter 15 Precision Care: Personalized Medicine in Chronic Obstructive Pulmonary Disease Management
• Chapter 16 Digital Health Solutions: Enhancing Medication Adherence in COPD Treatment
• Chapter 17 Clinical Trials and Regulatory Issues of Nanocarriers Employed in the Treatment of Chronic Obstructive Pulmonary Disease
• Chapter 18 Prospects of Advanced Drug Delivery Systems in Combating Chronic Obstructive Pulmonary Disease
• Index