Microcirculation in Cancer Metastasis
eBook - ePub

Microcirculation in Cancer Metastasis

  1. 328 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Microcirculation in Cancer Metastasis

About this book

Although mechanisms involved in the spread of cancer have been the subject of a major research endeavor over the past decade, metastatic tumors still account for significant clinical morbidity and the failure of cancer treatment. Not only are the vascular pathways the most common route for the dissemination of cancer cells, but interactions between the cells and the circulation act as important rate-regulators for the metastatic process.

This authoritative, multi-authored volume addresses the importance of microcirculation in cancer metastasis. The book begins with up-to-date reviews on the biology of endothelial cells and the structure and physiology of the normal and tumor microcirculations, and then emphasizes interactions between components of the microcirculation and cancer cells. Metastasis is discussed through chapters exploring the entry of cancer cells into the circulation, the biophysics and morphology of cancer cell traffic and arrest, interactions with host cells and the basement membranes, and angiogenesis. This fascinating book will interest oncologists, pathologists, and students of metastasis or the microcirculation.

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Yes, you can access Microcirculation in Cancer Metastasis by F. William Orr,Michael R. Buchanan,Leonard Weiss in PDF and/or ePUB format, as well as other popular books in Medicine & Oncology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2024
eBook ISBN
9781040277966
Topic
Medicine
Subtopic
Oncology

Table of contents

  1. Cover
  2. Title
  3. Copyright
  4. Preface
  5. The Editors
  6. Contributors
  7. Acknowledgment
  8. Table of Contents
  9. Chapter 1 Changes in the Extracellular Matrix During Transformation and Differentiation
  10. Chapter 2 Interactions of Tumor Cells with Basement Membranes
  11. Chapter 3 Endothelial Cell Function and Metastasis
  12. Chapter 4 Passage Across the Vascular Wall by Malignant Cells in Metastasis Formation
  13. Chapter 5 Entry of Cancer Cells into the Vasculature
  14. Chapter 6 Interactions Between Circulating Cancer Cells and Host Leukocytes
  15. Chapter 7 Platelets and Cancer Metastasis
  16. Chapter 8 The Thrombotic Consequences of Malignancy
  17. Chapter 9 The Biomechanics of Cancer Cell Traffic, Arrest, and Intravascular Destruction
  18. Chapter 10 The Role of Integrin Receptors in Tumor Cell Adhesion to the Microvasculature
  19. Chapter 11 Interactions Between Cancer Cells and the Endothelium
  20. Chapter 12 Selective Involvement of a Specific Sinusoidal Domain in Hepatic Metastasis
  21. Chapter 13 The Morphology of Cancer Cell Arrest and Extravasation
  22. Chapter 14 Fatty Acid Metabolism and Cancer Cell-Endothelial Cell Interactions
  23. Chapter 15 The Influence of Endothelial Injury and Inflammatory Processes on Metastasis
  24. Chapter 16 The Role of Vascularization in Tumor Metastasis
  25. Chapter 17 The Microcirculation of Tumors
  26. Index