Transformation of Human Diploid Fibroblasts
eBook - ePub

Transformation of Human Diploid Fibroblasts

Molecular and Genetic Mechanisms

  1. 304 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Transformation of Human Diploid Fibroblasts

Molecular and Genetic Mechanisms

About this book

This comprehensive publication draws together the important aspects of carcinogen-cell interaction. This interesting work describes the regulation of normal cell proliferation, cellular responses to carcinogen damage, the biologic consequences of cellular DNA modification, the structural and genomic changes resulting from carcinogen insult, and the possible involvement of such changes in the conversion of normal human fibroblasts to malignant cells. It presents current reviews with up-to-date literature references and provides critical information from leading investigators that is essential in understanding the biology of human cell transformation. This volume is especially useful to advanced students in genetic toxicology, molecular biologists, and all who are interested in the molecular and macromolecular changes in human cells leading to neoplasia.

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Yes, you can access Transformation of Human Diploid Fibroblasts by George E. Milo,Bruce C. Casto in PDF and/or ePUB format, as well as other popular books in Medicine & Medical Theory, Practice & Reference. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2024
eBook ISBN
9781040280119
Topic
Medicine
Subtopic
Medical Theory, Practice & Reference

Table of contents

  1. Cover
  2. Title
  3. Copyright
  4. Preface
  5. The Editors
  6. Contributors
  7. Table of Contents
  8. Chapter 1 Variations in Susceptibility to Initiation of Carcinogenesis During the Cell Cycle
  9. Chapter 2 Cell Cycle Regulation of DNA Repair Enzymes and Pathways
  10. Chapter 3 DNA Repair and Poly(ADP-ribose) Synthesis in Human Fibroblasts and Other Cell Types
  11. Chapter 4 Repair of O-Alkylation Damage in Human Cells
  12. Chapter 5 Ultraviolet Radiation-Induced Transformation of Human Cells
  13. Chapter 6 Biological Characterization and Quantification of Markers of Transformation of Human Fibroblasts
  14. Chapter 7 Mechanisms for Cell Transformation and Carcinogenesis by Genotoxic and Nongenotoxic Agents: Role of Sodium Saccharin
  15. Chapter 8 Relationship Between Bulky Carcinogen-DNA Modification: Carcinogenesis and Mutagenesis
  16. Chapter 9 Metabolism of Polyaromatic Hydrocarbons by Human Fibroblasts
  17. Chapter 10 DNA Adducts and Human Cell Transformation
  18. Chapter 11 Cytotoxicity and Cell Culture
  19. Chapter 12 Mechanisms by which Phorbol Ester Tumor Promoters Affect Gene Expression in Human Cells
  20. Chapter 13 Changes in Gene Expression Associated with Neoplastic Transformation of Human Fibroblasts: The Abundant Cellular Proteins
  21. Chapter 14 Differential Repair of Damage in Specific DNA Sequences of Human Cells
  22. Index