eBook - ePub
Advances in Prodrugs
Design and Therapeutic Applications
- 350 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Advances in Prodrugs
Design and Therapeutic Applications
About this book
Advances in Prodrugs: Design and Therapeutic Applications provides a versatile tool in prodrug design and development as well as a concrete perspective on clinical and preclinical studies currently available on prodrugs. The first part of this book discusses different chemical classes of prodrugs, with particular emphasis on metabolic pathways and mechanisms involved in the activation of their functional groups. The second part of the book covers therapeutic applications of prodrugs against the most discussed diseases, providing detailed discussion on recent achievements in the field. This book offers researchers involved in drug discovery key criteria for the successful development of prodrug-based therapeutic tools.Prodrugs are inactive drug precursors which undergo different chemical transformation by metabolic processes to provide pharmacologically active compounds. Prodrugs include a broad range of structurally diverse molecules employed for the treatment of several diseases.
- Highlights chemistry and pharmacology-related aspects, offering a versatile tool for readers involved in prodrug development and study
- Discusses in-depth treatment of several activation mechanisms and applications for disease treatments
- Covers a range of topics from basic contents, design, and mechanisms of actions to current applications in drugs
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Yes, you can access Advances in Prodrugs by Claudiu Trandafir Supuran,Andrea Angeli,Damiano Tanini in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Pharmacology. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Cover
- Front Matter
- Table of Contents
- Copyright
- Contributors
- Editors biography
- List of Illustrations
- List of Tables
- Chapter 1 : Prodrugs: General concepts and prodrug design in medicinal chemistry
- Chapter 2 : pH-sensitive prodrugs
- Chapter 3 : Enzyme-mediated activation of prodrugs
- Chapter 4 : Reactive oxygen species-responsive prodrugs
- Chapter 5 : Photoactivatable prodrugs
- Chapter 6 : Antibody-directed enzyme prodrug therapy (ADEPT)
- Chapter 7 : Self-assembling prodrugs
- Chapter 8 : Prodrug-based nanomedicines: A successful rationale to design novel and effective delivery strategies
- Chapter 9 : Hypoxia-activated prodrugs
- Chapter 10 : Antiviral and antiretroviral prodrugs
- Chapter 11 : Prodrugs for cancer therapy
- Chapter 12 : Prodrugs for neurodegenerative diseases
- Chapter 13 : Prodrugs in cardiovascular therapy
- Chapter 14 : Prodrugs for ocular diseases
- Chapter 15 : Antibacterial prodrugs
- Chapter 16 : Prodrugs on neglected tropical diseases and therapeutic advances
- Index
- A