
- 480 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
About this book
Cell and Gene Therapies for Neurologic Diseases, Volume 205 comprehensively covers the scientific background, translational efforts, clinical developments and registered biologics that have entered into clinical practice. Coverage includes types of therapies available and in development, and best practice uses for a variety of neurological disorders including Parkinson's, Huntington's, ALS, stroke, spinal cord RP, demyelination, and epilepsy. As the emergence of gene and cellular therapeutics has changed the clinical landscape for a variety of disorders, and is now ready to do so for neurological diseases, these therapeutic modalities currently complement, and may in time, supplant small molecule drugs.
- Summarizes advances in cell and gene therapy for neurological diseases
- Describes the therapies available and in development
- Includes surgical, ethical, and manufacturing considerations
- Identifies best practices for specific neurological diseases
- Covers Huntington's, Parkinson's, ALS, Stroke, Demyelination, epilepsy, and more
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Yes, you can access Cell and Gene Therapies for Neurologic Diseases by in PDF and/or ePUB format, as well as other popular books in Medicine & Neurology. We have over one million books available in our catalogue for you to explore.
Table of contents
- Cover image
- Table of Contents
- Series Page
- Copyright
- Handbook of Clinical Neurology 3rd Series
- Foreword
- Preface
- Contributors
- Section I: Cellular therapies
- Chapter 1: Introduction to stem cell biology and its role in treating neurologic disorders
- Chapter 2: History of cellular grafting for central nervous system repair—A clinical perspective
- Chapter 3: Autologous vs heterologous cell replacement strategies for Parkinson disease and other neurologic diseases
- Section II: Gene therapies
- Chapter 4: Viral vectors for gene delivery to the central nervous system
- Chapter 5: Viral and nonviral approaches
- Section III: General considerations (for cell and gene therapies)
- Chapter 6: Clinical/surgical considerations
- Chapter 7: Ethics of gene and cell therapy development for neurologic disorders
- Chapter 8: Clinical trial designs and endpoints
- Chapter 9: Immunology of cell and gene therapy approaches for neurologic diseases
- Chapter 10: Scaling of cell and gene therapies to population
- Chapter 11: The health economics of cell and gene therapies
- Section IV: Disease specific interventions using cells and genes
- Chapter 12: Disease-specific interventions: The use of cell and gene therapies for Parkinson disease
- Chapter 13: Using gene or cell therapies to treat Huntington's disease
- Chapter 14: Cell and gene therapy for amyotrophic lateral sclerosis
- Chapter 15: Gene and cell-based therapies for retinal and optic nerve disease
- Chapter 16: Disease-specific interventions using cell therapies for spinal cord disease/injury
- Chapter 17: Stem and progenitor cell-based therapy of myelin disorders
- Chapter 18: Cell and gene therapy in neuro-oncology
- Index