Pathophysiological Aspects of Proteases in Cancer
eBook - ePub

Pathophysiological Aspects of Proteases in Cancer

  1. 500 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Pathophysiological Aspects of Proteases in Cancer

About this book

Pathophysiological Aspects of Proteases in Cancer provides a comprehensive overview of the multifaceted field of proteases in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology. The book both gives insights on the general aspects of the role of proteases in cancer, their role as diagnostics and prognostics biomarkers, their impact on chemoresistance, and the future cutting-edge technologies like cocktail therapies and Cyber Knife technology. Given the breadth and depth of information covered in the respective contributions, the book will be immensely useful for researchers in oncology and working to identify targets for drug development.Multidisciplinary in scope, the book bridges the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry, making it a thought-provoking read for basic and applied scientists engaged in biomedical research. - Gives insight into the spectrum of proteases, protease inhibitors, and protease interactors involved at the cellular and molecular level in cancer development - Gives a comprehensive overview of the role of proteases in modulating cellular metabolism and chemoresistance to better understand how proteases play in early to the end point in cancer development and metastasis - Provides a multidisciplinary approach demonstrating the biochemical and signal transduction mechanisms associated with dysregulation of proteases, leading to the manifestation of various diseases - Highlights the roles and regulation of different types of proteases, as well as their synthetic and endogenous inhibitors - Bridges the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry

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Yes, you can access Pathophysiological Aspects of Proteases in Cancer by Sajal Chakraborti,Srijit Das,Cheorl-Ho Kim in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2024
eBook ISBN
9780443300998
Edition
0
Topic
Biological Sciences
Subtopic
Biology
Index
Biological Sciences

Table of contents

  1. Cover
  2. Front Matter
  3. Table of Contents
  4. Copyright
  5. Dedication
  6. Contributors
  7. Preface
  8. List of Illustrations
  9. List of Tables
  10. Chapter 1 : Pathophysiological aspects of calpains in cancer
  11. Chapter 2 : Mitochondrial proteases in cancer development and progression
  12. Chapter 3 : Proteases in head and neck cancer
  13. Chapter 4 : Matrix metalloproteinases and uveal melanoma
  14. Chapter 5 : Proteases in DNA damage, repair, and radioresistance: Cellular and molecular aspects
  15. Chapter 6 : Radiotherapy, proteases and gastric cancer: A complex interplay
  16. Chapter 7 : Matrix metalloproteases in the pathogenesis of hepatocarcinoma
  17. Chapter 8 : Exploring synthetic and natural compounds for cathepsin B: Mechanisms and therapy
  18. Chapter 9 : Kallikrein-related peptidase 3 (KLK3) as valuable biomarkers for prostate cancer
  19. Chapter 10 : Ubiquitin specific protease 3,7 in bone cancer and squamous cell carcinoma
  20. Chapter 11 : Serine protease: Structure, classification, mechanism and role in breast cancer
  21. Chapter 12 : Protease activator receptor-1 and matrix metalloproteinase-1 as prognostic factors and a novel therapeutic targets for gastric cancer
  22. Chapter 13 : Matrix metalloproteases as diagnostic and prognostic biomarkers in cancer
  23. Chapter 14 : From enzyme to predictors: Serine proteases in cancer diagnosis and prognosis
  24. Chapter 15 : Cathepsins as diagnostic and prognostic markers in oral cancer
  25. Chapter 16 : Role of kallikreins in prostate cancer
  26. Chapter 17 : Mechanistic aspects of serine protease as biomarkers in wound healing of lung cancer
  27. Chapter 18 : The role of acetylcholinesterase in cancer development and possible therapeutic applications
  28. Chapter 19 : Therapeutics of animal-derived compounds in proteases-induced cancer
  29. Chapter 20 : Molecular warriors: Proteases as sentinels in the war against cancer diagnosis and prognosis
  30. Chapter 21 : Serine proteases and their contribution to chemoresistance in cancer
  31. Chapter 22 : Cathepsins, chemoresistance, and cancer
  32. Chapter 23 : Matrix metalloproteinases, chemoresistance and cancer
  33. Chapter 24 : MMPs (-2 and -9)-mediated drug resistance and their reversal in gynecological cancer
  34. Chapter 25 : The link between trypsinogen and chymotrypsinogen in gastrointestinal cancer
  35. Chapter 26 : Role of proteasome in the development of chemoresistance in multiple myeloma
  36. Chapter 27 : Role of cysteine cathepsin and matrix metalloproteinases in progression and chemoresistance in ovarian and breast cancer
  37. Chapter 28 : Proteases, chemoresistance, and cancer
  38. Chapter 29 : Breaking barriers: Proteases as key players in cancer chemoresistance
  39. Chapter 30 : Matrix metalloproteasesā€“targeting low-molecular-weight compounds
  40. Chapter 31 : Evidence from clinical trials on synthetic protease inhibitors in oral, head, and neck cancer
  41. Chapter 32 : Synthetic protease inhibitors in endocrine and gastroenterology cancers: Results of clinical trials
  42. Chapter 33 : Side effects of synthetic protease inhibitors used in gynecology cancers
  43. Chapter 34 : The role of synthetic protease inhibitors in breast cancer
  44. Chapter 35 : Cathepsin-responsive nanomaterials for targeted delivery of malignant tumors
  45. Index
  46. A