
eBook - ePub
Synthetic Nucleic Acids as Inhibitors of Gene Expression
Mechanisms, Applications, and Therapeutic Implications
- 200 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Synthetic Nucleic Acids as Inhibitors of Gene Expression
Mechanisms, Applications, and Therapeutic Implications
About this book
In the post-genomic era we have, at our fingertips, an incredible array of genomic sequences from a multitude of complex organisms. There remains, however, the critical need to understand the precise roles individual genes play in complex biological milieu. Bringing together authoritative reviews by renowned international leaders, this book presents cutting-edge research on inhibitors of gene expression and nucleic acid-based drugs. With numerous charts, diagrams, and graphs, the book covers the subject from lab bench to cancer-related clinical trials, making it an up-to-date and critical resource. Coverage includes discussions of ribozyme subtypes, structure-function aspects, and therapeutic applications; DNAzymes, their various subtypes, kinetics and biochemistry, and applications in target validation. Lastly, the mechanisms and multiple therapeutic applications of double-stranded oligonucleotide decoys are described.
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Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access Synthetic Nucleic Acids as Inhibitors of Gene Expression by Levon Michael Khachigian in PDF and/or ePUB format, as well as other popular books in Medicine & Biotechnology in Medicine. We have over one million books available in our catalogue for you to explore.
Information
Topic
MedicineSubtopic
Biotechnology in MedicineTable of contents
- Cover
- Half Title
- Title Page
- Copyright Page
- Preface
- About the Editor
- Contributors
- About the Lead Authors
- Credits
- Table of Contents
- Chapter 1 Therapeutic Application of Ribozymes for Cardiovascular Disease
- Chapter 2 Development of Ribozymes as Cancer Therapeutics
- Chapter 3 RNA Interference: A Technology Based on an Ancient Gene Silencing Pathway
- Chapter 4 RNA-Cleaving DNA Enzymes in Gene Silencing: Room for Improvement?
- Chapter 5 Deoxyribozymes and Medical Innovation
- Chapter 6 Effect of Modifications on the Intracellular Activity of a DNA Enzyme
- Chapter 7 Potential Therapeutic Applications of DNA Enzymes and siRNAs against Viral and Cellular Genes
- Chapter 8 Use of DNAzymes for Target Gene Validation
- Chapter 9 DNAzymes Targeting Immediate-Early Genes as Inhibitors of Angiogenesis and Restenosis
- Chapter 10 Decoy Oligodeoxynucleotides as Viable Pharmaceutical Drugs
- Index