Viral Oncology

New Approaches to Molecular Cancer Therapeutics

Umesh Kumar, Deepak Parashar, Subodh Kumar

• Publisher: CRC Press
• Year: 2025
• eBook ISBN: 9781040329580
• Edition: 0
• Topic: Medicine
• Subtopic: Oncology

Viral Oncology: New Approaches to Molecular Cancer Therapeutics offers a comprehensive exploration of how viruses contribute to cancer development, bridging the gap between basic virology and clinical oncology. Featuring contributions from leading researchers, this authoritative text examines the mechanisms of viral oncogenesis, key oncogenic viruses, and the latest therapeutic strategies. The book highlights cutting-edge research on Human Papillomavirus (HPV), Epstein-Barr Virus (EBV), Hepatitis B and C, and other cancer-causing viruses, providing clinicians and researchers with critical insights into the prevention, diagnosis, and treatment of virus-induced cancers.

Ideal for oncologists, virologists, and molecular biologists, this text equips readers with both foundational knowledge and the latest advancements in the rapidly evolving field of viral oncology. Stay ahead in the field with this definitive guide to understanding and combating virusinduced malignancies. The volume explores the biology and pathology of oncogenic viruses, offering insights into novel therapeutic approaches, including immunotherapy and gene editing.

Viral Oncology: New Approaches to Molecular Cancer Therapeutics presents an in-depth and authoritative examination of how oncogenic viruses contribute to cancer development and progression, bridging the critical gap between foundational virology and clinical oncology. This volume brings together groundbreaking research from world-renowned scientists and clinicians who explore the complex mechanisms of viral oncogenesis, shedding light on both well-established and emerging viral agents, such as HPV, EBV, Hepatitis B and C, and Kaposi's Sarcoma-associated Herpesvirus (KSHV).

The text delves into the molecular processes through which these viruses initiate and sustain cancerous growth, offering insights into viral integration, immune evasion, and cellular transformation. With a focus on the latest developments in therapeutic strategies, Viral Oncology covers innovative approaches, including targeted molecular therapies, immunotherapies, gene editing techniques, and personalized medicine strategies aimed at halting virus-induced tumorigenesis.

Designed for a broad audience of oncologists, virologists, molecular biologists, and clinical researchers, this text provides a thorough understanding of the epidemiology, pathology, and treatment implications of viral oncology. It serves as an indispensable guide to the mechanisms of virus-driven cancers and how these insights are being translated into cutting-edge therapeutic interventions.

With its rich blend of cutting-edge science, clinical applications, and visionary outlook, Viral Oncology: New Approaches to Molecular Cancer Therapeutics is an essential resource for any professional involved in cancer research, diagnostics, and treatment. Whether you are a seasoned oncologist, virologist, or a researcher investigating the molecular basis of cancer, this book offers the latest knowledge and tools to effectively understand and combat virus-induced malignancies. Stay at the forefront of the rapidly evolving field of viral oncology with this comprehensive and forward-looking text – a definitive resource for understanding the interplay between viruses and cancer, and harnessing that knowledge for therapeutic innovation.

Table of contents

• Cover
• Half-Title Page
• Series Page
• Title Page
• Copyright Page
• Dedication
• Table of Contents
• Preface
• Acknowledgements
• About the Editors
• List of Contributors
• 1 Past, Present, and Future of Emerging Oncogenic Viral Infections
• 2 Global Epidemiology of Oncogenic Viral Infections
• 3 Host–Viral Interactions during Oncogenic Infections
• 4 Types of Viral Oncogenic Viral Diseases
• 5 Genetic Factors Influencing Oncogenic Viral Disease
• 6 Immune Response Associated with Oncogenic Viral Diseases
• 7 Immune Evasion Strategies by Oncogenic Viral Infections
• 8 Co-Infections Associated with Oncogenic Viral Disease
• 9 Oncogenic Viruses-Encoded microRNAs in Hepatotropic Oncogenic Viral Diseases
• 10 Hepatitis B Virus Infection: Epidemiology, Transmission, and Prevention
• 11 Cytomegalovirus (CMV): Diagnosis and Treatment
• 12 Causes, Symptoms, and Treatment of Epstein–Barr Virus Infection
• 13 Difficulties in Promptly Diagnosing and Treating Neonatal Herpes Simplex Virus Infection
• 14 Detection Methods in HPV-Related Cancers: Pathways and Targeted Therapeutic Strategies
• 15 Human T-Cell Leukemia Virus (HTLV)-Induced Carcinogenesis and Its Molecular Detection
• 16 Merkel cell Polyomavirus: Oncogenic Potential, Diagnosis, and Treatment
• 17 Developing New Molecular-Targeted Therapeutics, ‘from Gene to Drug’
• 18 The Medicinal Chemistry of Artificial Nucleic Acids and Therapeutic Oligonucleotides
• 19 Malignant Transformation In Vitro by Oncogenic Viruses
• 20 Laboratory Animal Model for Oncogenic Virus
• 21 Advances in Immunobiological Agents against Oncogenic Viral Diseases
• 22 CAR T-Cell Therapies against Viral Oncogenesis
• 23 miRNA-Associated Therapies for Oncogenic Viral Diseases
• 24 Vaccines: Future Prospects for Oncogenic Viral Diseases
• 25 Molecular Cancer Drug Discovery: Creative Interaction between Chemistry and Biology
• 26 Challenges and Future Perspectives of Using Antivirals in Viral Oncogenesis
• 27 Prevention and Therapeutic Approaches for Oncogenic Infections
• 28 Mesenchymal Stem Cells as Ideal Candidate for Delivering Oncolytic Viruses in the Tumour Microenvironment to Target Cancer Stem Cells
• 29 Viral Infections and Graft versus Host Disease Impeding Clinical Relevance of Hematopoietic Stem Cell Transplantation
• Index