- 220 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
T Cell Metabolism and Cancer Immunotherapy
About this book
T Cell Metabolism and Cancer Immunotherapy investigates the cellular regulation of T-cell immunity and tolerance. Most effort is being expended to develop and optimize strategies for utilizing highly reactive T lymphocytes for cell-based therapies. Because of the plasticity and potentially unlimited capacity for self-renewal, stem cell-derived T lymphocytes have great potential in the treatment of diseases including cancer.?
Despite great advancement in immunotherapy such as adoptive T cell transfer-based regimen, the clinical outcomes remain less satisfactory due to a variety of factors that lessen its therapeutic efficacy.? By determining the role and importance of T cell metabolism in the regulation of T lymphocytes that are related to the development and managements of aberrant immunity, T Cell Metabolism and Cancer Immunotherapy designs and develops novel and more effective strategies for improving regimens for patients with aberrant immunity.
Within ten chapters the content not only reveals targets of T cell metabolism as critical determinants of immune regulation, but also uncovers unique therapeutic opportunities to improve immunotherapy through targeting T cell metabolism. This fills a significant gap in the knowledge of scientists working in the field of onco-immunology/immunotherapy, and students learning about T cells, metabolism, immunomodulation, and immunotherapy
- Provides a summary of the current state-of-the-art, creating a valuable foundation for both established researchers and newcomers/students in the field in cancer immunotherapies
- Focuses on the investigation of cellular regulation of T-cell immunity and tolerance
- Defines the precise role and mechanism of T cell metabolism in modulating T cells and T cell-mediated immunity
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Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access T Cell Metabolism and Cancer Immunotherapy by Jianxun Song in PDF and/or ePUB format, as well as other popular books in Ciencias biológicas & Biología. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Front Cover
- T Cell Metabolism and Cancer Immunotherapy
- Copyright
- Cover image insert
- Aims and scope of series ``Breaking Tolerance to Anti-Cancer Cell-Mediated Immunotherapy´´
- About the Series Editor
- Aims and scope of the volume
- Volume Editor Biography
- Preface
- Contents
- Contributors
- Chapter 1: Modulating T cell metabolism to improve T cell therapy
- Chapter 2: Links between the DNA damage response and immune response in cancer
- Chapter 3: Improving adoptive T cell therapy by positive conversion of negative signaling
- Chapter 4: TGF-β in tumor microenvironment, metabolism, and immunotherapy
- Chapter 5: Targeting immunometabolism to improve cancer therapies
- Chapter 6: TCR-T cells for cancer immunotherapy
- Chapter 7: The combination of local treatment and immunotherapy
- Chapter 8: T cell metabolism and cancer immunotherapy
- Chapter 9: Exploring the interplay of kinases and transcription factors in immunometabolism
- Chapter 10: Targeting engineered bacteria to improve cancer immunotherapy
- Chapter 11: Salmonella: A bacterial warrior in cancer immunotherapy
- Chapter 12: Oncolytic virus for cancer immunotherapy
- Chapter 13: Advances in immunotherapy for colorectal cancer
- Index
- Back Cover