PARP as a Therapeutic Target
eBook - ePub

PARP as a Therapeutic Target

  1. 360 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

PARP as a Therapeutic Target

About this book

Recent research in cell death mechanisms has rekindled interest in PARP's (Poly (ADP-Ribose) Polymerase) intriguing role in necrosis and apoptosis. While the details of how PARP1 functions are still being elucidated, it has tremendous potential as a promising drug target. PARP inhibitors' dual actions of preventing cell death and abating inflammati

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Yes, you can access PARP as a Therapeutic Target by Jei Zhang in PDF and/or ePUB format, as well as other popular books in Medicine & Cell Biology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2002
eBook ISBN
9781040200322
Edition
0
Topic
Medicine
Subtopic
Cell Biology

Table of contents

  1. Cover
  2. Half Title
  3. Title Page
  4. Title Page
  5. Copyright Page
  6. Dedication
  7. Foreword
  8. Preface
  9. Contributors
  10. Table of Contents
  11. Chapter 1 Nervous System Functions of Poly(ADP-Ribose) Polymerase-1
  12. Chapter 2 Role of Poly(ADP-Ribose) Polymerase-1 in Neurologic Disorders
  13. Chapter 3 Involvement of PARP-1 and Poly(ADP-Ribosyl)ation in the Maintenance of
  14. Chapter 4 Functional Testing of Human PARP in Proliferation, Endotoxic Shock, and Radiosensitivity: A Genetic Rescue Study
  15. Chapter 5 PARP Inhibitors as Neuroprotective Agents for Brain Injury
  16. Chapter 6 PARP Inhibitors and Cardioprotection
  17. Chapter 7 Neuroprotection of the Retina with 3-Aminobenzamide, a PARP Inhibitor
  18. Chapter 8 Poly(ADP-Ribose) Polymerase Inhibitors and Acute Renal Failure
  19. Chapter 9 Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Shock and Inflammation
  20. Chapter 10 Clinical Development of the Nicotinamides and Benzamides Involving PARP as a Molecular Target
  21. Chapter 11 Chemoprotective Effect of a Novel PARP Inhibitor
  22. Chapter 12 Beneficial Effect of GPI 6150 Treatment in Multiple Animal Models of Diseases
  23. Chapter 13 Protecting Effect of PARP Inhibition on Ultraviolet Light–Induced Skin Damage
  24. Chapter 14 Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Diabetes Mellitus and Diabetic Vascular Dysfunction
  25. Chapter 15 Therapeutic Targeting of the PARPs: Future Challenges, Future Opportunities
  26. Index