Neurobiology of Huntington's Disease
eBook - ePub

Neurobiology of Huntington's Disease

Applications to Drug Discovery

  1. 338 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Neurobiology of Huntington's Disease

Applications to Drug Discovery

About this book

In 1993, the genetic mutation responsible for Huntington's disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse range of biochemical and genetic perturbations that see

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Yes, you can access Neurobiology of Huntington's Disease by Donald C. Lo,Robert E. Hughes in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2010
eBook ISBN
9781040200803

Table of contents

  1. Cover
  2. Half Title
  3. Title
  4. Copyright Page
  5. Dedication
  6. Contents
  7. Series Preface
  8. Preface
  9. Editors
  10. Contributors
  11. 1 Huntington’s Disease Clinical Features and Routes to Therapy
  12. 2 Huntington’s Disease Pathogenesis Mechanisms and Pathways
  13. 3 Protein Interactions and Target Discovery in Huntington’s Disease
  14. 4 Target Validation for Huntington’s Disease
  15. 5 High-Throughput and High-Content Screening for Huntington’s Disease Therapeutics
  16. 6 Value of Invertebrate Genetics and Biology to Develop Neuroprotective and Preventive Medicine in Huntington’s Disease
  17. 7 Mouse Models for Validating Preclinical Candidates for Huntington’s Disease
  18. 8 Pharmaceutical Development for Huntington’s Disease
  19. 9 RNA- and DNA-Based Therapies for Huntington’s Disease
  20. 10 Recombinant Intrabodies as Molecular Tools and Potential Therapeutics for Huntington’s Disease
  21. 11 Biomarkers to Enable the Development of Neuroprotective Therapies for Huntington’s Disease
  22. 12 Huntington’s Disease Clinical Experimental Therapeutics
  23. Index