Carotid Atherosclerotic Disease

Pathologic Basis for Treatment

Giuseppe Sangiorgi, David R. Holmes, Kenneth Rosenfield, L. Nelson Hopkins, Luigi Spagnoli

• Publisher: CRC Press
• Year: 2008
• Edition: 0
• eBook ISBN:
  9781040212257
• Topic: Medicine
• Subtopic: Cardiology

Carotid Atherosclerotic Disease: Pathologic Basis for Treatment reviews the natural history of carotid atherosclerotic plaque, this volume outlines different pathologic characteristics of asymptomatic and symptomatic carotid plaque. The authors provide a pathology-based rationale for assessment, risk stratification, and decision-making therapeutic strategy. They illustrate the impact of carotid plaque imaging and shed light on future advancement in gene therapy and carotid arterial wall repair. The book explores the shift from the old concept of "when" to treat-based on simple luminal narrowing, to the newer concept of "who should be treated"-based on plaque and patient characteristics.

Table of contents

• Cover
• Title Page
• Copyright Page
• Dedication
• Table of Contents
• Contributors
• Preface
• Acknowledgments
• Color Plates
• 1 Epidemiology of Carotid Atherosclerosis
• 2 Carotid Atherogenesis: From Experimental Models to Humans
• 3 Natural History of Carotid Atherosclerosis
• 4 Pathobiologic Determinants of Carotid Plaque Development
• 5 Anatomoclinical Correlation Between Symptomatic Plaques and Ischemic Damage
• 6 Risk Factors and the Morphology of Atherosclerotic Carotid Plaque
• 7 From Coronaries to Carotids: Shifting the Paradigm of Plaque Vulnerability
• 8 Imaging Modalities to Identify High-risk Subgroups
• 9 Carotid Echo Doppler: Diagnostic Tool or Impact on Indication and Treatment?
• 10 Role of Angiography and Intravascular Ultrasound
• 11 Optimal Utilization of Spiral Computed Tomography
• 12 Optimal Utilization of Magnetic Resonance Imaging
• 13 Impact of Plaque Analysis on Treatment Strategy
• 14 The Medical Treatment of Carotid Artery Disease
• 15 Contrast Ultrasound for Vasa Vasorum Imaging: Can We Improve Plaque Risk Stratification?
• 16 Registries and Trials of Carotid Artery Stenting Versus Carotid Endarterectomy
• 17 Is Any Stent Suitable for Any Lesion?
• 18 Protection Devices: A Must or An Option?
• 19 Carotid Angioplasty: Buenos Aires Experience, ENERI Medical Institute
• 20 The Role of Surgery for Carotid Atherosclerotic Disease
• 21 New Diagnostic Tools to Identify Vulnerable Carotid Plaques
• 22 Cell-based Approaches to Arterial Repair