Drinking Water and Health, Volume 9
eBook - PDF

Drinking Water and Health, Volume 9

Selected Issues in Risk Assessment

  1. 283 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Drinking Water and Health, Volume 9

Selected Issues in Risk Assessment

About this book

The National Research Council closes the landmark series Drinking Water and Health with Volume 9, published in two parts: Part I: DNA Adducts provides an overview of DNA adducts and their effects on human health, explores the techniques currently in use for detecting them, offers an outlook on future toxicity testing, and lists specific recommendations for action.Part II: Mixtures explores the issues surrounding multiple-chemical exposure from drinking water and reviews options for grouping compounds so their toxicity in mixtures can be reliably assessed. The book describes alternative approaches and considers the option of developing a modified "e;hazard index"e; for chemical compounds.

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Information

Year
1989
Edition
0
eBook ISBN
9780309542920

Table of contents

  1. Front Matter
  2. Part I: DNA Adducts
  3. Executive Summary
  4. 1 Biologic Significance of DNA Adducts and Protein Adducts
  5. 2 DNA-Adduct Technology
  6. 3 Conclusions and Recommendations
  7. Appendix A: Drinking Water Contaminant Candidates for Development of Baseline Data on Formation of DNA Adducts
  8. Glossary
  9. Biographical Sketches
  10. Part II: Mixtures
  11. Executive Summary
  12. 1 Introduction
  13. 2 Pharmacokinetics and the Risk Assessment of Drinking Water Contaminants
  14. 3 Risk Assessment of Mixtures of Systemic Toxicants in Drinking Water
  15. 4 Assessment of Exposure to Organophosphorus Conpounds, Carbamates, and Volatile Organic Chemicals
  16. 5 Acetylcholinesterase Inhibitors: Case Study of Mixtures of Contaminates with Similar Biologic Effects
  17. 6 Volatile Organic Compounds (VOCs): Risk Assessment of Mixtures of Potentially Carcinogenic Chemicals
  18. 7 Conclusions and Recommendations for Research
  19. Appendix A: An Approach for Risk Assessment of Volatile Organic Chemicals in Drinking Water That Uses Experimental Inhalation Data and a Physiologically Based Pharmacokinetic Model
  20. Appendix B: A Model Illustrating Synergism
  21. Appendix C: Models of Response: Dose Additivity and Response Additivity
  22. Biographical Sketches
  23. Part III: Cumulative Index
  24. Index

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