The Evolution of Imperfection
eBook - ePub

The Evolution of Imperfection

The Science of Why We Aren’t and Can’t Be Perfect

  1. English
  2. ePUB (mobile friendly)
  3. Available on iOS & Android
eBook - ePub

The Evolution of Imperfection

The Science of Why We Aren’t and Can’t Be Perfect

About this book

How understanding our genetic imperfections can change our view of evolution and enrich what it means to be human

If we start with the presumption that evolution is a constantly improving process, some aspects of our evolution just do not make sense. We have a high rate of genetic diseases, for example, and much of our DNA seems to be pointless. In The Evolution of Imperfection, Laurence Hurst explores our apparently rotten genetic luck.

Hurst, a leading authority on evolution and genetics, argues that our evolutionary imperfections proceed directly from two features: the difficulties of pregnancy and the fact that historically there are relatively few of us. In pregnancy, natural selection can favor chromosomes that kill embryos in species (including ours) that continuously receive resources from the mother. Most fertilized eggs don’t make it, and incompatibilities between the fetus and mother can lead to lethal disorders of pregnancy. The historically small population size enhances the role of chance, which in turn leads to both accumulation of unnecessary DNA and more mutation.

So what can save us? One answer may lie in genetic medicine, which has given us therapies that make killer conditions preventable and even curable.

Hurst suggests that our seeming imperfections could be the key to a new way to understand evolution itself. Looking at circumstances that seem to defy explanation, we might come to a richer understanding of how evolution really works, and what it means to be human.

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Yes, you can access The Evolution of Imperfection by Laurence D. Hurst in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Cover Page
  2. Title Page
  3. Copyright Page
  4. Dedication
  5. Epigraph
  6. Contents
  7. Preface
  8. Abbreviations
  9. 1. Introduction: The Problem of Perfection
  10. 2. The Problem of DNA
  11. 3. To Begin at the Beginning … How Adaptation Works
  12. 4. The Great Evolutionary Roulette Wheel
  13. 5. The Nearly Neutral Theory and the Problem of the Bloated Genome
  14. 6. Why Rare Diseases Aren’t Rare
  15. 7. Problems with Placentas, Pregnancy, and Perfection
  16. 8. The Evolutionary Fightback
  17. 9. The Medical Fightback
  18. Bibliography
  19. Index