Tight Junctions

Marcelino Cereijido, James M. Anderson

• Publisher: CRC Press
• Year: 2001
• eBook ISBN: 9781040203095
• Edition: 0
• Topic: Medicine
• Subtopic: Pharmacology

Physics of Optoelectronics focuses on the properties of optical fields and their interaction with matter. Understanding that lasers, LEDs, and photodetectors clearly exemplify this interaction, the author begins with an introduction to lasers, LEDs, and the rate equations, then describes the emission and detection processes.The book summarizes and reviews the mathematical background of the quantum theory embodied in the Hilbert space. These concepts highlight the abstract form of the linear algebra for vectors and operators, supplying the "pictures" that make the subject more intuitive. A chapter on dynamics includes a brief review of the formalism for discrete sets of particles and continuous media. It also covers the quantum theory necessary for the study of optical fields, transitions, and semiconductor gain. This volume supplements the description of lasers and LEDs by examining the fundamental nature of the light that these devices produce. It includes an analysis of quantized electromagnetic fields and illustrates inherent quantum noise in terms of Poisson and sub-Poisson statistics. It explains matter-light interaction in terms of time-dependent perturbation theory and Fermi's golden rule, and concludes with a detailed discussion of semiconductor emitters and detectors.

Table of contents

• Cover
• Half Title
• Title Page
• Copyright Page
• Preface
• The Editors
• Contributors
• Table of Contents
• 1 Introduction: Evolution of Ideas on the Tight Junction
• 2 Ultrastructure and Immunolabeling of the Tight Junction
• 3 Tight Junctions in Invertebrates
• 4 Tight Junction Permeability to Ions and Water
• 5 The Relationship Between Structure and Function of Tight Junctions
• 6 General Themes in Cell-Cell Junctions and Cell Adhesion
• 7 Protein Targeting Pathways and Sorting Signals in Epithelial Cells
• 8 Biogenesis of Epithelial Polarity and Tight Junctions
• 9 Optical Methods for the Study of Tight Junctions
• 10 Occludin and Claudins: Transmembrane Proteins of the Tight Junction
• 11 The Cytoplasmic Plaque Proteins of the Tight Junction
• 12 Organization and Regulation of the Tight Junction by the Actin-Myosin Cytoskeleton
• 13 Developmental Assembly of the Tight Junction
• 14 Tight Junctions and Cell Surface Lipid Polarity
• 15 Physiological Regulation of Tight Junction Permeability by Na+-Nutrient Cotransport
• 16 Extracellular Macromolecules
• 17 Intracellular Signaling in Classical and New Tight Junction Functions
• 18 Regulation of Tight Junction Permeability in the Mammary Gland
• 19 Unique Aspects of the Blood-Brain Barrier
• 20 Teleost Chloride Cell Tight Junctions: Environmental Salinity and Dynamic Structural Changes
• 21 Tight Junctions and Proteases
• 22 Claudins Mediate Specific Paracellular Fluxes in Vivo:
• 23 Microbial Pathogens That Affect Tight Junctions
• 24 Interactions between Clostridium perfringens Enterotoxin and Tight Junction Proteins
• 25 Ischemia-Induced Tight Junction Dysfunction in the Kidney
• 26 Tight Junctions in Intestinal Inflammation
• 27 Tight Junctions in Liver Disease
• 28 The Tight Junctions in the Testis, Epididymis, and Vas Deferens
• 29 Relationship between Tight Junctions and Leukocyte Transmigration
• 30 Ocular Tight Junctions in Health, Disease, and Glaucoma
• 31 Implications of Transport via the Paracellular Pathway on Drug Development
• 32
• 33 Functions of OSP/Claudin-11-Containing Parallel Tight Junctions: Implications from the Knockout Mouse
• Index